Flexeril and Roundback - a phase IV clinical study of FDA data
Summary:
Roundback is reported as a side effect among people who take Flexeril (cyclobenzaprine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zometa, and have Metastases to bone.
The phase IV clinical study analyzes which people have Roundback when taking Flexeril. It is created by eHealthMe based on reports of 34,789 people who have side effects when taking Flexeril from the FDA, and is updated regularly.
What is Flexeril?
Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,305 Flexeril users. Check the latest studies of Flexeril.
What is Roundback?
Roundback (abnormal rearward curvature of the spine) is found to be associated with 1,215 drugs and 730 conditions by eHealthMe. Check the latest studies of Roundback.
34,789 people reported to have side effects when taking Flexeril.
Among them, 169 people (0.49%) have Roundback.

Among these 169 people:
How long have people been on Flexeril when they have Roundback? *
What is the gender of people who have Roundback when taking Flexeril? *
What is the age of people who have Roundback when taking Flexeril? *
What are other drugs people take besides Flexeril? *
What are other side effects people have besides Roundback? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Flexeril and have Roundback?
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Related studies:
Effectiveness of, long term effects of, and alternative drugs to Flexeril:
- Flexeril (38,305 reports)
Roundback treatments and more:
- Roundback (3,242 reports)
How severe was Roundback and when was it recovered:
Expand to all the drugs that have ingredients of cyclobenzaprine hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flexeril:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Roundback:
- Fosamax side effect: Roundback (895 reports)
- Zometa side effect: Roundback (629 reports)
- Aredia side effect: Roundback (518 reports)
- Prednisone side effect: Roundback (515 reports)
- Aspirin side effect: Roundback (324 reports)
- Oxycontin side effect: Roundback (289 reports)
- Prilosec side effect: Roundback (271 reports)
- Alendronate sodium side effect: Roundback (259 reports)
- Coumadin side effect: Roundback (251 reports)
- Percocet side effect: Roundback (243 reports)
Browse all the drugs that are associated with Roundback:
- Roundback (1,215 drugs)
Common conditions associated with Roundback:
- Osteoporosis: 862 reports
- Osteopenia: 239 reports
- Multiple myeloma: 237 reports
- Hbp: 178 reports
- Rheumatoid arthritis: 167 reports
- Metastases to bone: 148 reports
- Pain relief: 141 reports
- Asthma: 127 reports
- Bronchial asthma: 125 reports
- Acupuncture and pain: 106 reports
Browse all the conditions that are associated with Roundback:
- Roundback (730 conditions)
Drugs similar to Flexeril and Roundback :
How the study uses the data?
The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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