Folic acid and Clostridium colitis - a phase IV clinical study of FDA data

Summary:

Clostridium colitis is reported as a side effect among people who take Folic acid (folic acid), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Methotrexate, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Clostridium colitis when taking Folic acid. It is created by eHealthMe based on reports of 162,497 people who have side effects when taking Folic acid from the FDA, and is updated regularly.

What is Folic acid?

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,027 Folic acid users. Check the latest studies of Folic acid.

What is Clostridium colitis?

Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 236 drugs and 503 conditions by eHealthMe. Check the latest studies of Clostridium colitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

162,497 people reported to have side effects when taking Folic acid.
Among them, 54 people (0.03%) have Clostridium colitis.

Could Folic acid cause Clostridium colitis?

Among these 54 people:

How long have people been on Folic acid when they have Clostridium colitis? *

What is the gender of people who have Clostridium colitis when taking Folic acid? *

female: 35.85 %
male: 64.15 %

What is the age of people who have Clostridium colitis when taking Folic acid? *

What are other drugs people take besides Folic acid? *

What are other side effects people have besides Clostridium colitis? *

Anaemia (lack of blood): 12 people, 22.22%
Thrombocytopenia (decrease of platelets in blood): 11 people, 20.37%
Pneumonia: 9 people, 16.67%
Nausea (feeling of having an urge to vomit): 9 people, 16.67%
Dyspnea (difficult or laboured breathing): 8 people, 14.81%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 8 people, 14.81%
Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 14.81%
Nausea And Vomiting: 7 people, 12.96%
Weakness: 7 people, 12.96%
Diarrhea: 7 people, 12.96%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.26%
Multiple Myeloma (cancer of the plasma cells): 5 people, 9.26%
Vitamin B Complex Deficiency: 4 people, 7.41%
Insomnia (sleeplessness): 4 people, 7.41%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 7.41%
Bladder Outlet Obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded): 4 people, 7.41%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 7.41%
Endocarditis (inflammation in heart muscle): 4 people, 7.41%
Glomerulonephritis Membranous (nephritis with inflammation of the capillary loops in the renal glomeruli): 3 people, 5.56%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Folic acid and have Clostridium colitis?

- Check whether Clostridium colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Folic acid:

Folic acid (165,027 reports)

Browse all side effects of Folic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium colitis:

Clostridium colitis (236 drugs)

Browse all the conditions that are associated with Clostridium colitis:

Clostridium colitis (503 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on folic acid (the active ingredients of Folic acid) and Folic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.