Fosamax and Osteochondroma - a phase IV clinical study of FDA data

Summary:

Osteochondroma is reported as a side effect among people who take Fosamax (alendronate sodium), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Alendronate Sodium, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Osteochondroma when taking Fosamax. It is created by eHealthMe based on reports of 104,411 people who have side effects when taking Fosamax from the FDA, and is updated regularly.

What is Fosamax?

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 105,452 Fosamax users. Check the latest studies of Fosamax.

What is Osteochondroma?

Osteochondroma (a type of benign tumour that consists of cartilage and bone) is found to be associated with 11 drugs and 62 conditions by eHealthMe. Check the latest studies of Osteochondroma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

104,411 people reported to have side effects when taking Fosamax.
Among them, 51 people (0.05%) have Osteochondroma.

Could Fosamax cause Osteochondroma?

Among these 51 people:

How long have people been on Fosamax when they have Osteochondroma? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 41.38 %
  • 2 - 5 years: 10.34 %
  • 5 - 10 years: 37.93 %
  • 10+ years: 10.34 %

What is the gender of people who have Osteochondroma when taking Fosamax? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Osteochondroma when taking Fosamax? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 64.1 %
  • 60+: 35.9 %

What are other drugs people take besides Fosamax? *

  1. Alendronate Sodium: 16 people, 31.37%
  2. Synthroid: 15 people, 29.41%
  3. Provera: 13 people, 25.49%
  4. Premarin: 13 people, 25.49%
  5. Zoloft: 10 people, 19.61%
  6. Flonase: 10 people, 19.61%
  7. Aredia: 10 people, 19.61%
  8. Advair Diskus 100/50: 9 people, 17.65%
  9. Boniva: 4 people, 7.84%
  10. Prempro: 4 people, 7.84%

What are other side effects people have besides Osteochondroma? *

  1. Femur Fracture: 37 people, 72.55%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 34 people, 66.67%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 33 people, 64.71%
  4. Intervertebral Disc Degeneration (spinal disc degeneration): 31 people, 60.78%
  5. Pain In Extremity: 30 people, 58.82%
  6. Fall: 29 people, 56.86%
  7. Constipation: 28 people, 54.90%
  8. High Blood Cholesterol: 26 people, 50.98%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 26 people, 50.98%
  10. Dizziness: 25 people, 49.02%

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 15 people, 29.41%
  2. Menopause (end of monthly cycles in women): 4 people, 7.84%
  3. Hyperthyroidism (over activity of the thyroid gland): 2 people, 3.92%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 3.92%
  5. High Blood Cholesterol: 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Fosamax and have Osteochondroma?

- Check whether Osteochondroma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fosamax:

Osteochondroma treatments and more:

How severe was Osteochondroma and when was it recovered:

Expand to all the drugs that have ingredients of alendronate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fosamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteochondroma:

Browse all the conditions that are associated with Osteochondroma:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on alendronate sodium (the active ingredients of Fosamax) and Fosamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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