Furosemide and Gingival hyperplasia - a phase IV clinical study of FDA data
Summary:
Gingival hyperplasia is reported as a side effect among people who take Furosemide (furosemide), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Metoprolol Tartrate, and have Dyslipidaemia.
The phase IV clinical study analyzes which people have Gingival hyperplasia when taking Furosemide. It is created by eHealthMe based on reports of 313,719 people who have side effects when taking Furosemide from the FDA, and is updated regularly.
What is Furosemide?
Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.
What is Gingival hyperplasia?
Gingival hyperplasia (overgrowth of gums) is found to be associated with 154 drugs and 263 conditions by eHealthMe. Check the latest studies of Gingival hyperplasia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
313,719 people reported to have side effects when taking Furosemide.
Among them, 15 people (0.0%) have Gingival hyperplasia.

Among these 15 people:
How long have people been on Furosemide when they have Gingival hyperplasia? *
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Gingival hyperplasia when taking Furosemide? *
- female: 33.33 %
- male: 66.67 %
What is the age of people who have Gingival hyperplasia when taking Furosemide? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 8.33 %
- 40-49: 25.0 %
- 50-59: 25.0 %
- 60+: 41.67 %
What are other drugs people take besides Furosemide? *
- Metoprolol Tartrate: 4 people, 26.67%
- Zetia: 3 people, 20.00%
- Erythromycin: 3 people, 20.00%
- Lipitor: 3 people, 20.00%
- Lisinopril: 3 people, 20.00%
- Neoral: 3 people, 20.00%
- Prograf: 2 people, 13.33%
- Azathioprine: 2 people, 13.33%
- Prednisolone: 2 people, 13.33%
- Plendil: 2 people, 13.33%
What are other side effects people have besides Gingival hyperplasia? *
- Gingival Bleeding (bleeding gums): 4 people, 26.67%
- Malaise (a feeling of general discomfort or uneasiness): 4 people, 26.67%
- Oedema Peripheral (superficial swelling): 4 people, 26.67%
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 3 people, 20.00%
- Drug Intolerance (drug sensitivity): 3 people, 20.00%
- Gingivitis (inflammation of gums): 3 people, 20.00%
- Gingival Pain (gum pain): 3 people, 20.00%
- Gingival Discoloration: 3 people, 20.00%
- Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 3 people, 20.00%
- Fever: 3 people, 20.00%
What are the existing conditions these people have? *
- Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 3 people, 20.00%
- Dyslipidaemia (abnormal amount of lipids): 3 people, 20.00%
- Oedema (fluid collection in tissue): 1 person, 6.67%
- Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 1 person, 6.67%
- Nausea (feeling of having an urge to vomit): 1 person, 6.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
- Dry Socket (inflammation in the socket of a tooth): 1 person, 6.67%
- Diabetes: 1 person, 6.67%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Furosemide and have Gingival hyperplasia?
- Check whether Gingival hyperplasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Furosemide:
- Furosemide (316,095 reports)
Gingival hyperplasia treatments and more:
- Gingival hyperplasia (1,228 reports)
How severe was Gingival hyperplasia and when was it recovered:
Expand to all the drugs that have ingredients of furosemide:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Furosemide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Gingival hyperplasia:
- Gingival hyperplasia (154 drugs)
Browse all the conditions that are associated with Gingival hyperplasia:
- Gingival hyperplasia (263 conditions)
Related publications that referenced our studies
- Raheel SA, Kujan OB, Tarakji B, Umar D, Ibrahim S, "Propranolol-induced gingival hyperplasia with Nager syndrome: A rare adverse drug reaction", Journal of advanced pharmaceutical technology & research, 2016 Jan .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
- Raheel SA, Kujan OB, Tarakji B, Umar D, Ibrahim S, "Propranolol-induced gingival hyperplasia with Nager syndrome: A rare adverse drug reaction", Journal of advanced pharmaceutical technology & research, 2016 Jan .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
How the study uses the data?
The study uses data from the FDA. It is based on furosemide (the active ingredients of Furosemide) and Furosemide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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