Gemcitabine and Aortic calcification - a phase IV clinical study of FDA data

Summary:

Aortic calcification is reported as a side effect among people who take Gemcitabine (gemcitabine), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Aortic calcification when taking Gemcitabine. It is created by eHealthMe based on reports of 31,291 people who have side effects when taking Gemcitabine from the FDA, and is updated regularly.

What is Gemcitabine?

Gemcitabine has active ingredients of gemcitabine. eHealthMe is studying from 31,337 Gemcitabine users. Check the latest studies of Gemcitabine.

What is Aortic calcification?

Aortic calcification (aortic calcification sign of heart valve disease) is found to be associated with 371 drugs and 383 conditions by eHealthMe. Check the latest studies of Aortic calcification.



On Jul, 05, 2026

31,291 people reported to have side effects when taking Gemcitabine.
Among them, 18 people (0.06%) have Aortic calcification.

Could Gemcitabine cause Aortic calcification?

Among these 18 people:

How long have people been on Gemcitabine when they have Aortic calcification? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Aortic calcification when taking Gemcitabine? *

  • female: 72.22 %
  • male: 27.78 %

What is the age of people who have Aortic calcification when taking Gemcitabine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.69 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 15.38 %
  • 60+: 76.92 %

What are other drugs people take besides Gemcitabine? *

  1. Zometa: 18 people, 100.00%
  2. Flexeril: 16 people, 88.89%
  3. Lorazepam: 15 people, 83.33%
  4. Alprazolam: 13 people, 72.22%
  5. Aredia: 12 people, 66.67%
  6. Neurontin: 11 people, 61.11%
  7. Celebrex: 10 people, 55.56%
  8. Toradol: 10 people, 55.56%
  9. Lovenox: 10 people, 55.56%
  10. Metoclopramide: 10 people, 55.56%

What are other side effects people have besides Aortic calcification? *

  1. Stress And Anxiety: 18 people, 100.00%
  2. Osteonecrosis Of Jaw (death of bone of jaw): 18 people, 100.00%
  3. Dyspnea (difficult or laboured breathing): 18 people, 100.00%
  4. Back Pain: 18 people, 100.00%
  5. Anaemia (lack of blood): 17 people, 94.44%
  6. Pain: 17 people, 94.44%
  7. Spinal Osteoarthritis (joint cartilage loss in spine): 17 people, 94.44%
  8. Hypoaesthesia (reduced sense of touch or sensation): 16 people, 88.89%
  9. Pain In Jaw: 16 people, 88.89%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 15 people, 83.33%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 11 people, 61.11%
  2. Bone Pain: 8 people, 44.44%
  3. Stress And Anxiety: 8 people, 44.44%
  4. Breast Cancer: 8 people, 44.44%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 44.44%
  6. Breast Cancer Metastatic: 6 people, 33.33%
  7. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 5 people, 27.78%
  8. Depression: 2 people, 11.11%
  9. Dyspnea (difficult or laboured breathing): 2 people, 11.11%
  10. Insomnia (sleeplessness): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Gemcitabine and have Aortic calcification?

- Check whether Aortic calcification is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gemcitabine:

Aortic calcification treatments and more:

How severe was Aortic calcification and when was it recovered:

Expand to all the drugs that have ingredients of gemcitabine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gemcitabine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic calcification:

Browse all the conditions that are associated with Aortic calcification:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on gemcitabine (the active ingredients of Gemcitabine) and Gemcitabine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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