Granix and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Granix (tbo-filgrastim), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Venclexta, and have Multiple myeloma.

The study is created by eHealthMe based on reports of 897 people who have side effects when taking Granix from the FDA, and is updated regularly.

What is Granix?

Granix has active ingredients of tbo-filgrastim. eHealthMe is studying from 897 Granix users. Check the latest studies of Granix.

On Aug, 05, 2026

897 people reported to have side effects when taking Granix.
Among them, 83 people (9.25%) died.

Among these 83 people:

How long have people been on Granix when they died? *

What is the gender of people who died when taking Granix? *

female: 53.85 %
male: 46.15 %

What is the age of people who died when taking Granix? *

What are other drugs people take besides Granix? *

What are other side effects people have before they died? *

Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 3.61%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 2.41%
Nausea (feeling of having an urge to vomit): 2 people, 2.41%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 2.41%
Wrist Deformity: 1 person, 1.20%
Diarrhea: 1 person, 1.20%
Hospitalisation: 1 person, 1.20%
Headache (pain in head): 1 person, 1.20%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 1 person, 1.20%
Febrile Neutropenia (fever with reduced white blood cells): 1 person, 1.20%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 12.05%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 7.23%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 4.82%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 3.61%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 3.61%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 3.61%
Pancreatic Carcinoma (pancreatic cancer): 3 people, 3.61%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 2 people, 2.41%
Nausea (feeling of having an urge to vomit): 2 people, 2.41%
Nausea And Vomiting: 2 people, 2.41%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Granix:

Granix (897 reports)

Expand to all the drugs that have ingredients of tbo-filgrastim:

Death and drugs with ingredients of tbo-filgrastim (129 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Granix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,116 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tbo-filgrastim (the active ingredients of Granix) and Granix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.