Humalog and Gallbladder operation - a phase IV clinical study of FDA data

Summary:

Gallbladder operation is reported as a side effect among people who take Humalog (insulin lispro recombinant), especially for people who are female, 60+ old, also take Lantus, and have Narcolepsy.

The phase IV clinical study analyzes which people have Gallbladder operation when taking Humalog. It is created by eHealthMe based on reports of 136,521 people who have side effects when taking Humalog from the FDA, and is updated regularly.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,126 Humalog users. Check the latest studies of Humalog.

What is Gallbladder operation?

Gallbladder operation is found to be associated with 358 drugs and 766 conditions by eHealthMe. Check the latest studies of Gallbladder operation.

On Feb, 09, 2026

136,521 people reported to have side effects when taking Humalog.
Among them, 45 people (0.03%) have Gallbladder operation.

Could Humalog cause Gallbladder operation?

Among these 45 people:

What is the gender of people who have Gallbladder operation when taking Humalog? *

female: 61.36 %
male: 38.64 %

What is the age of people who have Gallbladder operation when taking Humalog? *

What are other drugs people take besides Humalog? *

What are other side effects people have besides Gallbladder operation? *

Blood Glucose Increased: 14 people, 31.11%
Fall: 13 people, 28.89%
Pain: 12 people, 26.67%
High Blood Cholesterol: 11 people, 24.44%
Weakness: 10 people, 22.22%
High Blood Pressure: 10 people, 22.22%
Drug Ineffective: 10 people, 22.22%
Headache (pain in head): 9 people, 20.00%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 9 people, 20.00%
Stress And Anxiety: 9 people, 20.00%

What are the existing conditions these people have? *

Restless Leg Syndrome (a powerful urge to move your legs): 7 people, 15.56%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 15.56%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 15.56%
Drowsiness: 6 people, 13.33%
Insomnia (sleeplessness): 5 people, 11.11%
Sleep Disorder: 4 people, 8.89%
High Blood Pressure: 3 people, 6.67%
Osteoporosis (bones weak and more likely to break): 3 people, 6.67%
Depression: 3 people, 6.67%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Humalog and have Gallbladder operation?

- Check whether Gallbladder operation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Humalog:

Humalog (137,126 reports)

Browse all side effects of Humalog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder operation:

Gallbladder operation (358 drugs)

Browse all the conditions that are associated with Gallbladder operation:

Gallbladder operation (766 conditions)

Drugs similar to Humalog and Gallbladder operation :

How the study uses the data?

The study uses data from the FDA. It is based on insulin lispro recombinant (the active ingredients of Humalog) and Humalog (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.