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Humira and Ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Ventricular dysfunction is reported as a side effect among people who take Humira (adalimumab), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Psoriasis.

The phase IV clinical study analyzes which people have Ventricular dysfunction when taking Humira. It is created by eHealthMe based on reports of 758,421 people who have side effects when taking Humira from the FDA, and is updated regularly.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,393 Humira users. Check the latest studies of Humira.

What is Ventricular dysfunction?

Ventricular dysfunction (heart dysfunction) is found to be associated with 519 drugs and 549 conditions by eHealthMe. Check the latest studies of Ventricular dysfunction.

On Jan, 03, 2026

758,421 people reported to have side effects when taking Humira.
Among them, 36 people (0.0%) have Ventricular dysfunction.

Could Humira cause Ventricular dysfunction?

Among these 36 people:

How long have people been on Humira when they have Ventricular dysfunction? *

  • < 1 month: 46.15 %
  • 1 - 6 months: 7.69 %
  • 6 - 12 months: 15.38 %
  • 1 - 2 years: 23.08 %
  • 2 - 5 years: 7.69 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ventricular dysfunction when taking Humira? *

  • female: 45.71 %
  • male: 54.29 %

What is the age of people who have Ventricular dysfunction when taking Humira? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 30.43 %
  • 40-49: 13.04 %
  • 50-59: 8.7 %
  • 60+: 47.83 %

What are other drugs people take besides Humira? *

  1. Leflunomide: 3 people, 8.33%
  2. Simvastatin: 3 people, 8.33%
  3. Prednisolone: 3 people, 8.33%
  4. Metformin: 3 people, 8.33%
  5. Amlodipine: 2 people, 5.56%
  6. Folic Acid: 2 people, 5.56%
  7. Prednisone: 2 people, 5.56%
  8. Methotrexate: 2 people, 5.56%
  9. Enalapril Maleate: 1 person, 2.78%
  10. Hydrochlorothiazide: 1 person, 2.78%

What are other side effects people have besides Ventricular dysfunction? *

  1. Cardiac Arrest: 10 people, 27.78%
  2. Heart Attack: 8 people, 22.22%
  3. Acute Myocardial Infarction (acute heart attack): 7 people, 19.44%
  4. Pericarditis (inflammation of the pericardium): 7 people, 19.44%
  5. Ventricular Fibrillation (abnormally irregular heart rhythm): 6 people, 16.67%
  6. Dyspnea (difficult or laboured breathing): 4 people, 11.11%
  7. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 11.11%
  8. Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 11.11%
  9. Pain: 3 people, 8.33%
  10. Respiratory Disorder (respiratory disease): 3 people, 8.33%

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 10 people, 27.78%
  2. High Blood Pressure: 7 people, 19.44%
  3. Pain: 4 people, 11.11%
  4. Diabetes: 3 people, 8.33%
  5. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 5.56%
  6. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 5.56%
  7. Asthma: 1 person, 2.78%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.78%
  9. Cardiac Disorder: 1 person, 2.78%
  10. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Humira and have Ventricular dysfunction?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Humira:

Ventricular dysfunction treatments and more:

How severe was Ventricular dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of adalimumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular dysfunction:

Browse all the conditions that are associated with Ventricular dysfunction:

Drugs similar to Humira and Ventricular dysfunction :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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