Hydroxocobalamin and Peripheral swelling - a phase IV clinical study of FDA data

Summary:

Peripheral swelling is reported as a side effect among people who take Hydroxocobalamin (hydroxocobalamin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Paracetamol, and have High blood pressure.

The phase IV clinical study analyzes which people have Peripheral swelling when taking Hydroxocobalamin. It is created by eHealthMe based on reports of 4,242 people who have side effects when taking Hydroxocobalamin from the FDA, and is updated regularly.

What is Hydroxocobalamin?

Hydroxocobalamin has active ingredients of hydroxocobalamin. It is often used in pernicious anaemia. eHealthMe is studying from 4,273 Hydroxocobalamin users. Check the latest studies of Hydroxocobalamin.

What is Peripheral swelling?

Peripheral swelling is found to be associated with 2,181 drugs and 1,743 conditions by eHealthMe. Check the latest studies of Peripheral swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

4,242 people reported to have side effects when taking Hydroxocobalamin.
Among them, 78 people (1.84%) have Peripheral swelling.

Could Hydroxocobalamin cause Peripheral swelling?

Among these 78 people:

How long have people been on Hydroxocobalamin when they have Peripheral swelling? *

What is the gender of people who have Peripheral swelling when taking Hydroxocobalamin? *

female: 77.46 %
male: 22.54 %

What is the age of people who have Peripheral swelling when taking Hydroxocobalamin? *

What are other drugs people take besides Hydroxocobalamin? *

What are other side effects people have besides Peripheral swelling? *

Muscle Spasms (muscle contraction): 17 people, 21.79%
Pain In Extremity: 16 people, 20.51%
Back Pain: 15 people, 19.23%
Joint Swelling: 14 people, 17.95%
Fatigue (feeling of tiredness): 13 people, 16.67%
Sepsis (a severe blood infection that can lead to organ failure and death): 12 people, 15.38%
Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 12 people, 15.38%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 12 people, 15.38%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 12 people, 15.38%
Constipation: 12 people, 15.38%

What are the existing conditions these people have? *

High Blood Pressure: 16 people, 20.51%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 19.23%
Multiple Myeloma (cancer of the plasma cells): 15 people, 19.23%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 12 people, 15.38%
Neuropathy Peripheral (surface nerve damage): 12 people, 15.38%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 12 people, 15.38%
High Blood Cholesterol: 12 people, 15.38%
Macrocytosis (enlargement of red blood cells with near-constant haemoglobin concentration): 12 people, 15.38%
Nausea (feeling of having an urge to vomit): 12 people, 15.38%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxocobalamin and have Peripheral swelling?

- Check whether Peripheral swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxocobalamin:

Hydroxocobalamin (4,273 reports)

Browse all side effects of Hydroxocobalamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral swelling:

Peripheral swelling (2,181 drugs)

Browse all the conditions that are associated with Peripheral swelling:

Peripheral swelling (1,743 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxocobalamin (the active ingredients of Hydroxocobalamin) and Hydroxocobalamin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.