Ibrutinib and Drug level increased - a phase IV clinical study of FDA data

Summary:

Drug level increased is reported as a side effect among people who take Ibrutinib (ibrutinib), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Amaryl, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Drug level increased when taking Ibrutinib. It is created by eHealthMe based on reports of 13,522 people who have side effects when taking Ibrutinib from the FDA, and is updated regularly.

What is Ibrutinib?

Ibrutinib has active ingredients of ibrutinib. eHealthMe is studying from 13,529 Ibrutinib users. Check the latest studies of Ibrutinib.

What is Drug level increased?

Drug level increased is found to be associated with 874 drugs and 1,136 conditions by eHealthMe. Check the latest studies of Drug level increased.



On Aug, 07, 2026

13,522 people reported to have side effects when taking Ibrutinib.
Among them, 15 people (0.11%) have Drug level increased.

Could Ibrutinib cause Drug level increased?

Among these 15 people:

How long have people been on Ibrutinib when they have Drug level increased? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Drug level increased when taking Ibrutinib? *

  • female: 7.69 %
  • male: 92.31 %

What is the age of people who have Drug level increased when taking Ibrutinib? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.69 %
  • 50-59: 0.0 %
  • 60+: 92.31 %

What are other drugs people take besides Ibrutinib? *

  1. Zoloft: 1 person, 6.67%
  2. Wellbutrin: 1 person, 6.67%
  3. Tacrolimus: 1 person, 6.67%
  4. Prednisolone: 1 person, 6.67%
  5. Mycophenolate Mofetil: 1 person, 6.67%
  6. Losartan: 1 person, 6.67%
  7. Flomax: 1 person, 6.67%
  8. Coumadin: 1 person, 6.67%
  9. Bendamustine: 1 person, 6.67%
  10. Amaryl: 1 person, 6.67%

What are other side effects people have besides Drug level increased? *

  1. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 11 people, 73.33%
  2. Cerebral Aspergillosis (pus collection with swelling in brain): 11 people, 73.33%
  3. Hemiparesis (weakness on one side of the body): 10 people, 66.67%
  4. Pulmonary Alveolar Haemorrhage (acute bleeding): 8 people, 53.33%
  5. Cough: 8 people, 53.33%
  6. Dyspnea (difficult or laboured breathing): 8 people, 53.33%
  7. Infectious Pleural Effusion (infectious fluid in the lung): 7 people, 46.67%
  8. Dizziness: 7 people, 46.67%
  9. Balance Disorder: 7 people, 46.67%
  10. Pulmonary Mass: 7 people, 46.67%

What are the existing conditions these people have? *

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 11 people, 73.33%
  2. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 9 people, 60.00%
  3. Cerebral Aspergillosis (pus collection with swelling in brain): 2 people, 13.33%
  4. Mantle Cell Lymphoma Recurrent (cancer of lymphocytes, a type of white blood cell- recurrent): 1 person, 6.67%
  5. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 6.67%
  6. Ischaemic Neuropathy (functional disturbance or pathological change in the peripheral nervous system due to inadequate supply of blood): 1 person, 6.67%
  7. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 6.67%
  8. Central Nervous System Lymphoma (cancer of central nervous system forms in lymph tissue): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Ibrutinib and have Drug level increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibrutinib:

Drug level increased treatments and more:

How severe was Drug level increased and when was it recovered:

Expand to all the drugs that have ingredients of ibrutinib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibrutinib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug level increased:

Browse all the conditions that are associated with Drug level increased:


How the study uses the data?

The study uses data from the FDA. It is based on ibrutinib (the active ingredients of Ibrutinib) and Ibrutinib (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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