1. Home
  2. Analysis
  3. Ibuprofen
  4. Bladder-discomfort

Ibuprofen and Bladder discomfort - a phase IV clinical study of FDA data

Summary:

Bladder discomfort is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are male, 50-59 old, have been taking the drug for 6 - 12 months also take Prednisone, and have Ankylosing spondylitis.

The phase IV clinical study analyzes which people have Bladder discomfort when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Bladder discomfort?

Bladder discomfort is found to be associated with 206 drugs and 305 conditions by eHealthMe. Check the latest studies of Bladder discomfort.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 59 people (0.02%) have Bladder discomfort.

Could Ibuprofen cause Bladder discomfort?

Among these 59 people:

How long have people been on Ibuprofen when they have Bladder discomfort? *

  • < 1 month: 11.11 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 88.89 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bladder discomfort when taking Ibuprofen? *

  • female: 36.54 %
  • male: 63.46 %

What is the age of people who have Bladder discomfort when taking Ibuprofen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.88 %
  • 40-49: 24.39 %
  • 50-59: 58.54 %
  • 60+: 12.2 %

What are other drugs people take besides Ibuprofen? *

  1. Prednisone: 18 people, 30.51%
  2. Cosentyx: 16 people, 27.12%
  3. Naproxen: 13 people, 22.03%
  4. Sulfasalazine: 12 people, 20.34%
  5. Percocet: 10 people, 16.95%
  6. Gabapentin: 10 people, 16.95%
  7. Seroquel: 8 people, 13.56%
  8. Flexeril: 8 people, 13.56%
  9. Ketoconazole: 8 people, 13.56%
  10. Aciphex: 8 people, 13.56%

What are other side effects people have besides Bladder discomfort? *

  1. Fatigue (feeling of tiredness): 27 people, 45.76%
  2. Diarrhea: 25 people, 42.37%
  3. Urinary Tract Infection: 24 people, 40.68%
  4. Nasopharyngitis (inflammation of the nasopharynx): 22 people, 37.29%
  5. Burning Sensation: 22 people, 37.29%
  6. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 22 people, 37.29%
  7. Dizziness: 22 people, 37.29%
  8. Spinal Disorder (disease of spine a back bone): 22 people, 37.29%
  9. Neck Pain: 21 people, 35.59%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 20 people, 33.90%

What are the existing conditions these people have? *

  1. Ankylosing Spondylitis (type of arthritis affecting the spine): 17 people, 28.81%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 13.56%
  3. Insomnia (sleeplessness): 6 people, 10.17%
  4. Sleep Disorder: 6 people, 10.17%
  5. Prostate Cancer: 3 people, 5.08%
  6. High Blood Pressure: 3 people, 5.08%
  7. Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 3.39%
  8. Breast Cancer: 1 person, 1.69%
  9. Cardiac Failure: 1 person, 1.69%
  10. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 1.69%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Bladder discomfort?

- Check whether Bladder discomfort is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Bladder discomfort treatments and more:

How severe was Bladder discomfort and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder discomfort:

Browse all the conditions that are associated with Bladder discomfort:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.