Ibuprofen and Bladder dysfunction - a phase IV clinical study of FDA data

Summary:

Bladder dysfunction is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 60+ old, also take Compazine, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Bladder dysfunction when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,269 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Bladder dysfunction?

Bladder dysfunction is found to be associated with 249 drugs and 274 conditions by eHealthMe. Check the latest studies of Bladder dysfunction.

On Feb, 12, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 45 people (0.02%) have Bladder dysfunction.

Could Ibuprofen cause Bladder dysfunction?

Among these 45 people:

What is the gender of people who have Bladder dysfunction when taking Ibuprofen? *

female: 68.89 %
male: 31.11 %

What is the age of people who have Bladder dysfunction when taking Ibuprofen? *

What are other drugs people take besides Ibuprofen? *

What are other side effects people have besides Bladder dysfunction? *

Fatigue (feeling of tiredness): 26 people, 57.78%
Weakness: 22 people, 48.89%
Nausea (feeling of having an urge to vomit): 15 people, 33.33%
Pain In Extremity: 15 people, 33.33%
Dizziness: 13 people, 28.89%
Stress And Anxiety: 12 people, 26.67%
Joint Pain: 12 people, 26.67%
Mobility Decreased (ability to move is reduced): 11 people, 24.44%
Urinary Tract Infection: 11 people, 24.44%
Neck Pain: 10 people, 22.22%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 26.67%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 10 people, 22.22%
Depression: 9 people, 20.00%
Anaemia (lack of blood): 8 people, 17.78%
Metastases To Bone (cancer spreads to bone): 8 people, 17.78%
Osteoporosis (bones weak and more likely to break): 8 people, 17.78%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 8 people, 17.78%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 15.56%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 7 people, 15.56%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 5 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Bladder dysfunction?

- Check whether Bladder dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Ibuprofen (245,269 reports)

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder dysfunction:

Bladder dysfunction (249 drugs)

Browse all the conditions that are associated with Bladder dysfunction:

Bladder dysfunction (274 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.