Ibuprofen and Diffuse interstitial lung disease - a phase IV clinical study of FDA data

Summary:

Diffuse interstitial lung disease is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Omeprazole, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Diffuse interstitial lung disease when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Diffuse interstitial lung disease?

Diffuse interstitial lung disease (group of lung diseases affecting the interstitium) is found to be associated with 232 drugs and 802 conditions by eHealthMe. Check the latest studies of Diffuse interstitial lung disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 21, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 86 people (0.04%) have Diffuse interstitial lung disease.

Could Ibuprofen cause Diffuse interstitial lung disease?

Among these 86 people:

How long have people been on Ibuprofen when they have Diffuse interstitial lung disease? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Diffuse interstitial lung disease when taking Ibuprofen? *

  • female: 27.71 %
  • male: 72.29 %

What is the age of people who have Diffuse interstitial lung disease when taking Ibuprofen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.53 %
  • 30-39: 1.27 %
  • 40-49: 3.8 %
  • 50-59: 3.8 %
  • 60+: 88.61 %

What are other drugs people take besides Ibuprofen? *

  1. Omeprazole: 56 people, 65.12%
  2. Simvastatin: 52 people, 60.47%
  3. Levothyroxine Sodium: 49 people, 56.98%
  4. Amoxicillin: 47 people, 54.65%
  5. Aspirin: 43 people, 50.00%
  6. Amlodipine: 41 people, 47.67%
  7. Perindopril Erbumine: 14 people, 16.28%
  8. Amlodipine Besylate: 9 people, 10.47%
  9. Zocor: 6 people, 6.98%
  10. Acetylsalicylic Acid: 6 people, 6.98%

What are other side effects people have besides Diffuse interstitial lung disease? *

  1. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 69 people, 80.23%
  2. Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 59 people, 68.60%
  3. Oropharyngeal Pain: 59 people, 68.60%
  4. Coughing Up Blood: 59 people, 68.60%
  5. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 59 people, 68.60%
  6. Acute Kidney Failure: 58 people, 67.44%
  7. Weight Decreased: 57 people, 66.28%
  8. Lower Respiratory Tract Infection: 57 people, 66.28%
  9. Weakness: 56 people, 65.12%
  10. Drug Eruption (adverse drug reaction of the skin): 56 people, 65.12%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 8.14%
  2. Joint Pain: 6 people, 6.98%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 5.81%
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 5.81%
  5. High Blood Pressure: 3 people, 3.49%
  6. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 3.49%
  7. Nausea And Vomiting: 2 people, 2.33%
  8. Nausea (feeling of having an urge to vomit): 2 people, 2.33%
  9. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 2.33%
  10. Influenza Like Illness: 2 people, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Diffuse interstitial lung disease?

- Check whether Diffuse interstitial lung disease is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Diffuse interstitial lung disease treatments and more:

How severe was Diffuse interstitial lung disease and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diffuse interstitial lung disease:

Browse all the conditions that are associated with Diffuse interstitial lung disease:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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