Ibuprofen and Enterocolitis haemorrhagic - a phase IV clinical study of FDA data

Summary:

Enterocolitis haemorrhagic is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Amoxicillin, and have High blood pressure.

The phase IV clinical study analyzes which people have Enterocolitis haemorrhagic when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Enterocolitis haemorrhagic?

Enterocolitis haemorrhagic (bleeding and inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon) is found to be associated with 181 drugs and 390 conditions by eHealthMe. Check the latest studies of Enterocolitis haemorrhagic.



On Aug, 13, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 32 people (0.01%) have Enterocolitis haemorrhagic.

Could Ibuprofen cause Enterocolitis haemorrhagic?

Among these 32 people:

How long have people been on Ibuprofen when they have Enterocolitis haemorrhagic? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Enterocolitis haemorrhagic when taking Ibuprofen? *

  • female: 53.33 %
  • male: 46.67 %

What is the age of people who have Enterocolitis haemorrhagic when taking Ibuprofen? *

  • 0-1: 0.0 %
  • 2-9: 3.33 %
  • 10-19: 30.0 %
  • 20-29: 3.33 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 10.0 %
  • 60+: 53.33 %

What are other drugs people take besides Ibuprofen? *

  1. Amoxicillin: 9 people, 28.12%
  2. Methotrexate: 4 people, 12.50%
  3. Ramipril: 4 people, 12.50%
  4. Clarithromycin: 4 people, 12.50%
  5. Prednisone: 4 people, 12.50%
  6. Rocephin: 4 people, 12.50%
  7. Metformin: 3 people, 9.38%
  8. Pantoprazole: 3 people, 9.38%
  9. Paracetamol: 3 people, 9.38%
  10. Combivent: 2 people, 6.25%

What are other side effects people have besides Enterocolitis haemorrhagic? *

  1. Haemolytic Anaemia (anaemia due to haemolysis): 9 people, 28.12%
  2. Thrombocytopenia (decrease of platelets in blood): 9 people, 28.12%
  3. Diarrhea: 5 people, 15.62%
  4. Abdominal Pain: 4 people, 12.50%
  5. White Blood Cell Count Increased: 3 people, 9.38%
  6. Anaemia (lack of blood): 3 people, 9.38%
  7. Colitis (inflammation of colon): 3 people, 9.38%
  8. Rectal Haemorrhage (bleeding from anus): 3 people, 9.38%
  9. Intestinal Ischaemia (decreased supply of oxygenated blood to the intestines): 3 people, 9.38%
  10. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 3 people, 9.38%

What are the existing conditions these people have? *

  1. Jaw Fracture: 4 people, 12.50%
  2. High Blood Pressure: 4 people, 12.50%
  3. Diabetes: 3 people, 9.38%
  4. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 9.38%
  5. Metastatic Neoplasm (spreadable cancer tumour): 3 people, 9.38%
  6. Pneumonia: 2 people, 6.25%
  7. Back Disorder: 2 people, 6.25%
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 6.25%
  9. Encephalopathy (functioning of the brain is affected by some agent or condition): 2 people, 6.25%
  10. Lymphoma (cancer that begins in immune system cells): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Enterocolitis haemorrhagic?

- Check whether Enterocolitis haemorrhagic is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Enterocolitis haemorrhagic treatments and more:

How severe was Enterocolitis haemorrhagic and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enterocolitis haemorrhagic:

Browse all the conditions that are associated with Enterocolitis haemorrhagic:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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