Ibuprofen and Haemoglobinuria - a phase IV clinical study of FDA data

Summary:

Haemoglobinuria is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Tylenol, and have Toothaches.

The phase IV clinical study analyzes which people have Haemoglobinuria when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Haemoglobinuria?

Haemoglobinuria (the presence of free haemoglobin in the urine) is found to be associated with 84 drugs and 250 conditions by eHealthMe. Check the latest studies of Haemoglobinuria.

On Aug, 11, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 15 people (0.01%) have Haemoglobinuria.

Among these 15 people:

How long have people been on Ibuprofen when they have Haemoglobinuria? *

What is the gender of people who have Haemoglobinuria when taking Ibuprofen? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Haemoglobinuria when taking Ibuprofen? *

What are other drugs people take besides Ibuprofen? *

What are other side effects people have besides Haemoglobinuria? *

Abdominal Discomfort: 6 people, 40.00%
Abdominal Pain: 6 people, 40.00%
Pigment Nephropathy (disease of the kidneys): 5 people, 33.33%
Hypoplastic Anaemia (anaemia resulting from inadequately functioning bone marrow): 5 people, 33.33%
Injury: 5 people, 33.33%
Intravascular Haemolysis (intravascular rupture of red blood cells with the release of haemoglobin and the cellular constituents into the plasma, or liquid portion of whole blood): 5 people, 33.33%
Dehydration (dryness resulting from the removal of water): 4 people, 26.67%
Kidney Enlargement: 3 people, 20.00%
Nausea (feeling of having an urge to vomit): 3 people, 20.00%
Normochromic Normocytic Anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits): 3 people, 20.00%

What are the existing conditions these people have? *

Toothaches (tooth pain): 6 people, 40.00%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%
Foetal Arrhythmia (abnormal rate or rhythm of the foetus heartbeat): 2 people, 13.33%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.67%
Urinary Tract Infection: 1 person, 6.67%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 6.67%
Stress And Anxiety: 1 person, 6.67%
Nausea And Vomiting: 1 person, 6.67%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Haemoglobinuria?

- Check whether Haemoglobinuria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Ibuprofen (245,270 reports)

Haemoglobinuria treatments and more:

Haemoglobinuria (1,366 reports)

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemoglobinuria:

Haemoglobinuria (84 drugs)

Browse all the conditions that are associated with Haemoglobinuria:

Haemoglobinuria (250 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.