Ibuprofen and Hypercoagulation - a phase IV clinical study of FDA data

Summary:

Hypercoagulation is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Nuvaring, and have Birth control.

The phase IV clinical study analyzes which people have Hypercoagulation when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,269 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Hypercoagulation?

Hypercoagulation (increased tendency for clotting of the blood) is found to be associated with 398 drugs and 537 conditions by eHealthMe. Check the latest studies of Hypercoagulation.

On Jun, 15, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 76 people (0.03%) have Hypercoagulation.

Among these 76 people:

How long have people been on Ibuprofen when they have Hypercoagulation? *

What is the gender of people who have Hypercoagulation when taking Ibuprofen? *

female: 89.47 %
male: 10.53 %

What is the age of people who have Hypercoagulation when taking Ibuprofen? *

What are other drugs people take besides Ibuprofen? *

What are other side effects people have besides Hypercoagulation? *

Pulmonary Embolism (blockage of the main artery of the lung): 41 people, 53.95%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 41 people, 53.95%
Dyspnea (difficult or laboured breathing): 25 people, 32.89%
Dizziness: 18 people, 23.68%
Migraine (headache): 17 people, 22.37%
Multiple Injuries: 14 people, 18.42%
Pulmonary Infarction (death of a small area of lung): 13 people, 17.11%
Depression: 12 people, 15.79%
Thrombocytopenia (decrease of platelets in blood): 12 people, 15.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 14.47%

What are the existing conditions these people have? *

Birth Control: 26 people, 34.21%
Heavy Or Prolong Menstrual Bleeding: 5 people, 6.58%
Acne (skin problems that cause pimples): 4 people, 5.26%
Hypomania (a mild form of mania, marked by elation and hyperactivity): 4 people, 5.26%
Oedema (fluid collection in tissue): 4 people, 5.26%
Ovarian Cysts (fluid filled sacs of the ovary): 4 people, 5.26%
Migraine (headache): 4 people, 5.26%
Protein S Deficiency: 3 people, 3.95%
Menstruation Irregular: 3 people, 3.95%
Breast Cancer: 3 people, 3.95%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Hypercoagulation?

- Check whether Hypercoagulation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Ibuprofen (245,269 reports)

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercoagulation:

Hypercoagulation (398 drugs)

Browse all the conditions that are associated with Hypercoagulation:

Hypercoagulation (537 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.