Ibuprofen and Ipf - a phase IV clinical study of FDA data

Summary:

Ipf is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Ipf when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,256 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Ipf?

Ipf is found to be associated with 2,162 drugs and 2,245 conditions by eHealthMe. Check the latest studies of Ipf.



On Sep, 07, 2025

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 746 people (0.31%) have Ipf.

Could Ibuprofen cause Ipf?

Among these 746 people:

How long have people been on Ibuprofen when they have Ipf? *

  • < 1 month: 50.0 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 28.57 %
  • 5 - 10 years: 7.14 %
  • 10+ years: 0.0 %

What is the gender of people who have Ipf when taking Ibuprofen? *

  • female: 77.14 %
  • male: 22.86 %

What is the age of people who have Ipf when taking Ibuprofen? *

  • 0-1: 0.0 %
  • 2-9: 1.48 %
  • 10-19: 0.93 %
  • 20-29: 0.74 %
  • 30-39: 1.3 %
  • 40-49: 54.17 %
  • 50-59: 11.32 %
  • 60+: 30.06 %

What are other drugs people take besides Ibuprofen? *

  1. Prednisone: 412 people, 55.23%
  2. Humira: 410 people, 54.96%
  3. Simponi: 393 people, 52.68%
  4. Stelara: 388 people, 52.01%
  5. Actemra: 388 people, 52.01%
  6. Enbrel: 387 people, 51.88%
  7. Cimzia: 382 people, 51.21%
  8. Xeljanz: 381 people, 51.07%
  9. Methotrexate: 377 people, 50.54%
  10. Folic Acid: 377 people, 50.54%

What are other side effects people have besides Ipf? *

  1. Fatigue (feeling of tiredness): 406 people, 54.42%
  2. Nausea (feeling of having an urge to vomit): 405 people, 54.29%
  3. Diarrhea: 377 people, 50.54%
  4. Joint Pain: 373 people, 50.00%
  5. Pneumonia: 365 people, 48.93%
  6. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 354 people, 47.45%
  7. Arthropathy: 346 people, 46.38%
  8. High Blood Pressure: 342 people, 45.84%
  9. General Physical Health Deterioration (weak health status): 341 people, 45.71%
  10. Abdominal Discomfort: 336 people, 45.04%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 500 people, 67.02%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 372 people, 49.87%
  3. Psoriasis (immune-mediated disease that affects the skin): 226 people, 30.29%
  4. Stress And Anxiety: 99 people, 13.27%
  5. Adenomatous Polyposis Coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine): 98 people, 13.14%
  6. Indigestion: 79 people, 10.59%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 75 people, 10.05%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 54 people, 7.24%
  9. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 45 people, 6.03%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 36 people, 4.83%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Ipf?

- Check whether Ipf is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Ipf treatments and more:

  • Ipf (79,191 reports)

How severe was Ipf and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Ibuprofen side effects:

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ipf:

Browse all the drugs that are associated with Ipf:

  • Ipf (2,162 drugs)

Common conditions associated with Ipf:

Browse all the conditions that are associated with Ipf:

  • Ipf (2,245 conditions)

Drugs similar to Ibuprofen and Ipf :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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