Ibuprofen and Petit mal epilepsy - a phase IV clinical study of FDA data

Summary:

Petit mal epilepsy is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Valium, and have Seizures.

The phase IV clinical study analyzes which people have Petit mal epilepsy when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Petit mal epilepsy?

Petit mal epilepsy (absence seizure) is found to be associated with 346 drugs and 612 conditions by eHealthMe. Check the latest studies of Petit mal epilepsy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 74 people (0.03%) have Petit mal epilepsy.

Could Ibuprofen cause Petit mal epilepsy?

Among these 74 people:

How long have people been on Ibuprofen when they have Petit mal epilepsy? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Petit mal epilepsy when taking Ibuprofen? *

  • female: 71.43 %
  • male: 28.57 %

What is the age of people who have Petit mal epilepsy when taking Ibuprofen? *

  • 0-1: 3.45 %
  • 2-9: 8.62 %
  • 10-19: 15.52 %
  • 20-29: 5.17 %
  • 30-39: 12.07 %
  • 40-49: 24.14 %
  • 50-59: 3.45 %
  • 60+: 27.59 %

What are other drugs people take besides Ibuprofen? *

  1. Valium: 15 people, 20.27%
  2. Keppra: 10 people, 13.51%
  3. Ativan: 9 people, 12.16%
  4. Avonex: 9 people, 12.16%
  5. Magnesium: 7 people, 9.46%
  6. Gocovri: 7 people, 9.46%
  7. Melatonin: 7 people, 9.46%
  8. Paracetamol: 7 people, 9.46%
  9. Percocet: 7 people, 9.46%
  10. Rytary: 7 people, 9.46%

What are other side effects people have besides Petit mal epilepsy? *

  1. Fatigue (feeling of tiredness): 14 people, 18.92%
  2. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 11 people, 14.86%
  3. Memory Loss: 10 people, 13.51%
  4. Weakness: 10 people, 13.51%
  5. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 13.51%
  6. Drowsiness: 9 people, 12.16%
  7. High Blood Pressure: 8 people, 10.81%
  8. Breathing - Slowed Or Stopped: 8 people, 10.81%
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 8.11%
  10. Consciousness - Decreased: 6 people, 8.11%

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 14 people, 18.92%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 13 people, 17.57%
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 7 people, 9.46%
  4. Dyskinesia (abnormality or impairment of voluntary movement): 7 people, 9.46%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 9.46%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 6 people, 8.11%
  7. Immunodeficiency Common Variable: 4 people, 5.41%
  8. Respiratory Disorder (respiratory disease): 3 people, 4.05%
  9. Pelvic Inflammatory Disease: 3 people, 4.05%
  10. Fever: 2 people, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Petit mal epilepsy?

- Check whether Petit mal epilepsy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Petit mal epilepsy treatments and more:

How severe was Petit mal epilepsy and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Petit mal epilepsy:

Browse all the conditions that are associated with Petit mal epilepsy:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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