Ibuprofen and Scleritis - a phase IV clinical study of FDA data

Summary:

Scleritis is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Itraconazole, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Scleritis when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Scleritis?

Scleritis (inflammation of sclera) is found to be associated with 217 drugs and 329 conditions by eHealthMe. Check the latest studies of Scleritis.



On Jul, 23, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 53 people (0.02%) have Scleritis.

Could Ibuprofen cause Scleritis?

Among these 53 people:

How long have people been on Ibuprofen when they have Scleritis? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Scleritis when taking Ibuprofen? *

  • female: 64 %
  • male: 36 %

What is the age of people who have Scleritis when taking Ibuprofen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.33 %
  • 30-39: 13.95 %
  • 40-49: 9.3 %
  • 50-59: 37.21 %
  • 60+: 37.21 %

What are other drugs people take besides Ibuprofen? *

  1. Itraconazole: 10 people, 18.87%
  2. Zometa: 9 people, 16.98%
  3. Prednisone: 9 people, 16.98%
  4. Spironolactone: 9 people, 16.98%
  5. Xalatan: 9 people, 16.98%
  6. Aspirin: 9 people, 16.98%
  7. Flonase: 9 people, 16.98%
  8. Flexeril: 9 people, 16.98%
  9. Topamax: 9 people, 16.98%
  10. Timolol Maleate: 8 people, 15.09%

What are other side effects people have besides Scleritis? *

  1. Eye Pain: 22 people, 41.51%
  2. Ocular Hyperaemia (an abnormally large amount of blood in eye): 19 people, 35.85%
  3. Photophobia (extreme sensitivity to light): 16 people, 30.19%
  4. Conjunctivitis (pink eye): 14 people, 26.42%
  5. Vision Blurred: 14 people, 26.42%
  6. Atelectasis (partial or complete collapse of the lung): 13 people, 24.53%
  7. Dizziness: 13 people, 24.53%
  8. Anaemia (lack of blood): 13 people, 24.53%
  9. Drug Ineffective: 10 people, 18.87%
  10. Discomfort: 10 people, 18.87%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 9 people, 16.98%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 11.32%
  3. Inflammation: 5 people, 9.43%
  4. Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 7.55%
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 3 people, 5.66%
  6. Rosacea (a skin condition that causes facial redness): 3 people, 5.66%
  7. Eye Disorder: 3 people, 5.66%
  8. Hepatitis C: 3 people, 5.66%
  9. Corneal Ulcers And Infections: 3 people, 5.66%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Scleritis?

- Check whether Scleritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Scleritis treatments and more:

How severe was Scleritis and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Scleritis:

Browse all the conditions that are associated with Scleritis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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