Ibuprofen and Trismus - a phase IV clinical study of FDA data

Summary:

Trismus is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Trismus when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Trismus?

Trismus (reduced opening of the jaws) is found to be associated with 592 drugs and 764 conditions by eHealthMe. Check the latest studies of Trismus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 83 people (0.03%) have Trismus.

Among these 83 people:

How long have people been on Ibuprofen when they have Trismus? *

What is the gender of people who have Trismus when taking Ibuprofen? *

female: 57.69 %
male: 42.31 %

What is the age of people who have Trismus when taking Ibuprofen? *

What are other drugs people take besides Ibuprofen? *

What are other side effects people have besides Trismus? *

Dizziness: 24 people, 28.92%
Nausea (feeling of having an urge to vomit): 22 people, 26.51%
Nausea And Vomiting: 21 people, 25.30%
Fever: 18 people, 21.69%
Pain In Extremity: 18 people, 21.69%
Stress And Anxiety: 17 people, 20.48%
Cellulitis (infection under the skin): 14 people, 16.87%
High Blood Pressure: 13 people, 15.66%
Joint Pain: 13 people, 15.66%
Gait Disturbance: 12 people, 14.46%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 15.66%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 8.43%
Nausea (feeling of having an urge to vomit): 6 people, 7.23%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 7.23%
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 6 people, 7.23%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 6 people, 7.23%
Depression: 6 people, 7.23%
Temporomandibular Joint Syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress): 5 people, 6.02%
Oropharyngeal Pain: 5 people, 6.02%
Stress And Anxiety: 4 people, 4.82%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Trismus?

- Check whether Trismus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Ibuprofen (245,270 reports)

Trismus treatments and more:

Trismus (6,560 reports)

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Trismus:

Trismus (592 drugs)

Browse all the conditions that are associated with Trismus:

Trismus (764 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.