Indocin and Angina pectoris aggravated - a phase IV clinical study of FDA data

Summary:

Angina pectoris aggravated is reported as a side effect among people who take Indocin (indomethacin), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Vioxx, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Angina pectoris aggravated when taking Indocin. It is created by eHealthMe based on reports of 4,328 people who have side effects when taking Indocin from the FDA, and is updated regularly.

What is Indocin?

Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.

What is Angina pectoris aggravated?

Angina pectoris aggravated (chest pain due to ischemia of the heart muscle) is found to be associated with 1,391 drugs and 656 conditions by eHealthMe. Check the latest studies of Angina pectoris aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

4,328 people reported to have side effects when taking Indocin.
Among them, 50 people (1.16%) have Angina pectoris aggravated.

Could Indocin cause Angina pectoris aggravated?

Among these 50 people:

How long have people been on Indocin when they have Angina pectoris aggravated? *

What is the gender of people who have Angina pectoris aggravated when taking Indocin? *

female: 10 %
male: 90 %

What is the age of people who have Angina pectoris aggravated when taking Indocin? *

What are other drugs people take besides Indocin? *

What are other side effects people have besides Angina pectoris aggravated? *

Coronary Artery Atherosclerosis (life-threatening blockages in the arteries of your heart): 20 people, 40.00%
Weakness: 18 people, 36.00%
Dyspnea (difficult or laboured breathing): 17 people, 34.00%
Joint Pain: 16 people, 32.00%
Chest Pain: 16 people, 32.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 16 people, 32.00%
Fatigue (feeling of tiredness): 15 people, 30.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 30.00%
Acute Myocardial Infarction (acute heart attack): 15 people, 30.00%
Stress And Anxiety: 14 people, 28.00%

What are the existing conditions these people have? *

High Blood Cholesterol: 5 people, 10.00%
Thyroid Diseases: 3 people, 6.00%
Joint Pain: 3 people, 6.00%
Cardiac Disorder: 3 people, 6.00%
Headache (pain in head): 3 people, 6.00%
Indigestion: 3 people, 6.00%
Rosacea (a skin condition that causes facial redness): 3 people, 6.00%
Migraine (headache): 2 people, 4.00%
Stress Symptoms: 2 people, 4.00%
High Blood Pressure: 2 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Indocin and have Angina pectoris aggravated?

- Check whether Angina pectoris aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Indocin:

Indocin (4,559 reports)

Browse all side effects of Indocin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (1,391 drugs)

Browse all the conditions that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (656 conditions)

Related publications that referenced our studies

Mantarro S, Tuccori M, Pasqualetti G, Tognini S, Montagnani S, Monzani F, Blandizzi C, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", BMC geriatrics, 2012 Nov .
Mantarro S, Tuccori M, Pasqualetti G, Tognini S, Montagnani S, Monzani F, Blandizzi C, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", BMC geriatrics, 2012 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on indomethacin (the active ingredients of Indocin) and Indocin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.