Isoniazid and Mydriasis - a phase IV clinical study of FDA data

Summary:

Mydriasis is reported as a side effect among people who take Isoniazid (isoniazid), especially for people who are female, 60+ old, also take Pyrazinamide, and have Latent tuberculosis.

The phase IV clinical study analyzes which people have Mydriasis when taking Isoniazid. It is created by eHealthMe based on reports of 19,852 people who have side effects when taking Isoniazid from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Mydriasis?

Mydriasis (a dilation of the pupil) is found to be associated with 796 drugs and 1,151 conditions by eHealthMe. Check the latest studies of Mydriasis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

19,852 people reported to have side effects when taking Isoniazid.
Among them, 20 people (0.1%) have Mydriasis.

Among these 20 people:

What is the gender of people who have Mydriasis when taking Isoniazid? *

female: 65 %
male: 35 %

What is the age of people who have Mydriasis when taking Isoniazid? *

What are other drugs people take besides Isoniazid? *

What are other side effects people have besides Mydriasis? *

Blood Creatine Phosphokinase Increased: 5 people, 25.00%
Myoglobin Blood Increased (presence of myoglobin in blood increased): 5 people, 25.00%
Headache (pain in head): 4 people, 20.00%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 4 people, 20.00%
Depressed Level Of Consciousness: 3 people, 15.00%
Agitation (state of anxiety or nervous excitement): 3 people, 15.00%
Akathisia (a movement disorder characterized by a feeling of inner restlessness): 3 people, 15.00%
Psychomotor Hyperactivity (feelings of extreme restlessness): 3 people, 15.00%
Confusional State: 3 people, 15.00%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 15.00%

What are the existing conditions these people have? *

Latent Tuberculosis (hidden tuberculosis): 4 people, 20.00%
Meningitis Tuberculous (a bacterial infection of the membranes covering the brain and spinal cord (meninges)): 2 people, 10.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 10.00%
Systemic Mycosis (fungal infections of the body): 1 person, 5.00%
Pericarditis Tuberculous (tuberculosis infection of the pericardial membrane (pericardium) covering the heart): 1 person, 5.00%
Panniculitis (inflammation of the subcutaneous fat): 1 person, 5.00%
Pain: 1 person, 5.00%
Neuralgia (pain in one or more nerves): 1 person, 5.00%
Immunodeficiency Disorders: 1 person, 5.00%
Hiv Infection: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and have Mydriasis?

- Check whether Mydriasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoniazid:

Isoniazid (20,174 reports)

Mydriasis treatments and more:

Mydriasis (15,532 reports)

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mydriasis:

Mydriasis (796 drugs)

Browse all the conditions that are associated with Mydriasis:

Mydriasis (1,151 conditions)

Related publications that referenced our studies

Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .
Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on isoniazid (the active ingredients of Isoniazid) and Isoniazid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.