Isoniazid and Synovitis - a phase IV clinical study of FDA data

Summary:

Synovitis is reported as a side effect among people who take Isoniazid (isoniazid), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Humira, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Synovitis when taking Isoniazid. It is created by eHealthMe based on reports of 19,852 people who have side effects when taking Isoniazid from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Synovitis?

Synovitis (inflammation of the synovial membrane) is found to be associated with 693 drugs and 512 conditions by eHealthMe. Check the latest studies of Synovitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

19,852 people reported to have side effects when taking Isoniazid.
Among them, 22 people (0.11%) have Synovitis.

Among these 22 people:

How long have people been on Isoniazid when they have Synovitis? *

What is the gender of people who have Synovitis when taking Isoniazid? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Synovitis when taking Isoniazid? *

What are other drugs people take besides Isoniazid? *

What are other side effects people have besides Synovitis? *

Diarrhea: 12 people, 54.55%
Drug Ineffective: 12 people, 54.55%
Nausea And Vomiting: 11 people, 50.00%
Psoriasis (immune-mediated disease that affects the skin): 11 people, 50.00%
Drug Intolerance (drug sensitivity): 11 people, 50.00%
Nausea (feeling of having an urge to vomit): 11 people, 50.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 10 people, 45.45%
Red Blood Cell Sedimentation Rate Increased: 10 people, 45.45%
Fever: 10 people, 45.45%
Dizziness: 10 people, 45.45%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 68.18%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 9 people, 40.91%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 13.64%
Latent Tuberculosis (hidden tuberculosis): 3 people, 13.64%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 13.64%
Seasonal Allergy (allergic condition due to certain season): 2 people, 9.09%
Rhinitis Perennial (an inflammatory condition of the nose characterized by nasal obstruction, sneezing, itching): 2 people, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.09%
Spondyloarthropathy (any joint disease of the vertebral column): 1 person, 4.55%
Pustular Psoriasis (raised bumps on the skin that are filled with pus): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and have Synovitis?

- Check whether Synovitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoniazid:

Isoniazid (20,174 reports)

Synovitis treatments and more:

Synovitis (24,130 reports)

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Synovitis:

Synovitis (693 drugs)

Browse all the conditions that are associated with Synovitis:

Synovitis (512 conditions)

Related publications that referenced our studies

Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .
Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on isoniazid (the active ingredients of Isoniazid) and Isoniazid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.