Ispaghula and Hypokalemia - a phase IV clinical study of FDA data

Summary:

Hypokalemia is reported as a side effect among people who take Ispaghula (blond psyllium), especially for people who are female, 60+ old, also take Mirabegron, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Hypokalemia when taking Ispaghula. It is created by eHealthMe based on reports of 735 people who have side effects when taking Ispaghula from the FDA, and is updated regularly.

What is Ispaghula?

Ispaghula has active ingredients of blond psyllium. eHealthMe is studying from 737 Ispaghula users. Check the latest studies of Ispaghula.

What is Hypokalemia?

Hypokalemia (low potassium) is found to be associated with 2,096 drugs and 3,091 conditions by eHealthMe. Check the latest studies of Hypokalemia.

On Jul, 09, 2026

735 people reported to have side effects when taking Ispaghula.
Among them, 16 people (2.18%) have Hypokalemia.

Among these 16 people:

What is the gender of people who have Hypokalemia when taking Ispaghula? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Hypokalemia when taking Ispaghula? *

What are other drugs people take besides Ispaghula? *

What are other side effects people have besides Hypokalemia? *

Fall: 15 people, 93.75%
Electrocardiogram Qt Prolonged: 15 people, 93.75%
Blood Sodium Decreased: 9 people, 56.25%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 2 people, 12.50%
Wound: 1 person, 6.25%
Oedema Peripheral (superficial swelling): 1 person, 6.25%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 1 person, 6.25%
Febrile Neutropenia (fever with reduced white blood cells): 1 person, 6.25%
Fainting (loss of consciousness and postural tone): 1 person, 6.25%
Dehydration (dryness resulting from the removal of water): 1 person, 6.25%

What are the existing conditions these people have? *

Type 2 Diabetes: 1 person, 6.25%
Oedema Peripheral (superficial swelling): 1 person, 6.25%
Necrosis (the death of body tissue): 1 person, 6.25%
Nausea (feeling of having an urge to vomit): 1 person, 6.25%
High Blood Pressure: 1 person, 6.25%
Constipation: 1 person, 6.25%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 6.25%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 6.25%
Bronchial Obstruction (blockage of the breathing passages to the lungs): 1 person, 6.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Ispaghula and have Hypokalemia?

- Check whether Hypokalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ispaghula:

Ispaghula (737 reports)

Hypokalemia treatments and more:

Hypokalemia (72,277 reports)

Browse all side effects of Ispaghula:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypokalemia:

Hypokalemia (2,096 drugs)

Browse all the conditions that are associated with Hypokalemia:

Hypokalemia (3,091 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on blond psyllium (the active ingredients of Ispaghula) and Ispaghula (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.