Istodax and Nausea and vomiting - a phase IV clinical study of FDA data

Summary:

Nausea and vomiting is reported as a side effect among people who take Istodax (romidepsin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Pantoprazole, and have Peripheral t-cell lymphoma unspecified.

The phase IV clinical study analyzes which people have Nausea and vomiting when taking Istodax. It is created by eHealthMe based on reports of 1,053 people who have side effects when taking Istodax from the FDA, and is updated regularly.

What is Istodax?

Istodax has active ingredients of romidepsin. eHealthMe is studying from 1,054 Istodax users. Check the latest studies of Istodax.

What is Nausea and vomiting?

Nausea and vomiting is found to be associated with 3,694 drugs and 5,743 conditions by eHealthMe. Check the latest studies of Nausea and vomiting.

On Jul, 09, 2026

1,053 people reported to have side effects when taking Istodax.
Among them, 44 people (4.18%) have Nausea and vomiting.

Could Istodax cause Nausea and vomiting?

Among these 44 people:

How long have people been on Istodax when they have Nausea and vomiting? *

What is the gender of people who have Nausea and vomiting when taking Istodax? *

female: 48.15 %
male: 51.85 %

What is the age of people who have Nausea and vomiting when taking Istodax? *

What are other drugs people take besides Istodax? *

What are other side effects people have besides Nausea and vomiting? *

Nausea (feeling of having an urge to vomit): 36 people, 81.82%
Fatigue (feeling of tiredness): 18 people, 40.91%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 16 people, 36.36%
Thrombocytopenia (decrease of platelets in blood): 14 people, 31.82%
Diarrhea: 11 people, 25.00%
Anaemia (lack of blood): 10 people, 22.73%
Headache (pain in head): 8 people, 18.18%
Fever: 8 people, 18.18%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 15.91%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 15.91%

What are the existing conditions these people have? *

Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 11 people, 25.00%
T-Cell Lymphoma (a blood cell cancer): 6 people, 13.64%
Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 4 people, 9.09%
Hiv Infection: 3 people, 6.82%
Breast Cancer: 2 people, 4.55%
Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 2 people, 4.55%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 4.55%
Lymphoma (cancer that begins in immune system cells): 2 people, 4.55%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 4.55%
Oedema Peripheral (superficial swelling): 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Istodax and have Nausea and vomiting?

- Check whether Nausea and vomiting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Istodax:

Istodax (1,054 reports)

Browse all side effects of Istodax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea and vomiting:

Nausea and vomiting (3,694 drugs)

Browse all the conditions that are associated with Nausea and vomiting:

Nausea and vomiting (5,743 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on romidepsin (the active ingredients of Istodax) and Istodax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.