Isturisa and Drowsiness - a phase IV clinical study of FDA data

Summary:

Drowsiness is reported as a side effect among people who take Isturisa (osilodrostat phosphate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Eliquis, and have Pituitary-dependent cushing's syndrome.

The phase IV clinical study analyzes which people have Drowsiness when taking Isturisa. It is created by eHealthMe based on reports of 1,083 people who have side effects when taking Isturisa from the FDA, and is updated regularly.

What is Isturisa?

Isturisa has active ingredients of osilodrostat phosphate. eHealthMe is studying from 1,085 Isturisa users. Check the latest studies of Isturisa.

What is Drowsiness?

Drowsiness is found to be associated with 2,866 drugs and 4,796 conditions by eHealthMe. Check the latest studies of Drowsiness.

On Jul, 02, 2026

1,083 people reported to have side effects when taking Isturisa.
Among them, 28 people (2.59%) have Drowsiness.

Among these 28 people:

How long have people been on Isturisa when they have Drowsiness? *

What is the gender of people who have Drowsiness when taking Isturisa? *

female: 75 %
male: 25 %

What is the age of people who have Drowsiness when taking Isturisa? *

What are other drugs people take besides Isturisa? *

What are other side effects people have besides Drowsiness? *

Fatigue (feeling of tiredness): 20 people, 71.43%
Nausea (feeling of having an urge to vomit): 9 people, 32.14%
Weakness: 8 people, 28.57%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 25.00%
Weight Decreased: 6 people, 21.43%
Weight Increased: 5 people, 17.86%
Headache (pain in head): 5 people, 17.86%
Pain: 5 people, 17.86%
Diarrhea: 5 people, 17.86%
Muscle Aches (muscle pain): 4 people, 14.29%

What are the existing conditions these people have? *

Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 14 people, 50.00%
Cushing's Syndrome (obesity, a rounded face, increased fat): 7 people, 25.00%
Neuropathy Peripheral (surface nerve damage): 3 people, 10.71%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 10.71%
Diabetes: 3 people, 10.71%
High Blood Pressure: 2 people, 7.14%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 7.14%
Erection Problems: 1 person, 3.57%
Asthma: 1 person, 3.57%
Constipation: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Isturisa and have Drowsiness?

- Check whether Drowsiness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isturisa:

Isturisa (1,085 reports)

Drowsiness treatments and more:

Drowsiness (269,040 reports)

Browse all side effects of Isturisa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drowsiness:

Drowsiness (2,866 drugs)

Browse all the conditions that are associated with Drowsiness:

Drowsiness (4,796 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on osilodrostat phosphate (the active ingredients of Isturisa) and Isturisa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.