Keflex and Shock - a phase IV clinical study of FDA data

Summary:

Shock is reported as a side effect among people who take Keflex (cephalexin), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Bactrim, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Shock when taking Keflex. It is created by eHealthMe based on reports of 14,902 people who have side effects when taking Keflex from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Shock?

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin) is found to be associated with 1,213 drugs and 1,755 conditions by eHealthMe. Check the latest studies of Shock.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

14,902 people reported to have side effects when taking Keflex.
Among them, 33 people (0.22%) have Shock.

Among these 33 people:

How long have people been on Keflex when they have Shock? *

What is the gender of people who have Shock when taking Keflex? *

female: 63.33 %
male: 36.67 %

What is the age of people who have Shock when taking Keflex? *

What are other drugs people take besides Keflex? *

What are other side effects people have besides Shock? *

Fever: 15 people, 45.45%
Nausea (feeling of having an urge to vomit): 14 people, 42.42%
Nausea And Vomiting: 14 people, 42.42%
Rashes (redness): 12 people, 36.36%
Headache (pain in head): 12 people, 36.36%
Pain In Extremity: 12 people, 36.36%
Ascites (accumulation of fluid in the abdominal cavity): 12 people, 36.36%
Chills (felling of cold): 12 people, 36.36%
Dyspnea (difficult or laboured breathing): 11 people, 33.33%
Weakness: 11 people, 33.33%

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 7 people, 21.21%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 21.21%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 12.12%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.09%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 9.09%
Pain: 3 people, 9.09%
Rickets (softening of bones): 2 people, 6.06%
Impaired Gastric Emptying: 2 people, 6.06%
Infusion Site Irritation: 2 people, 6.06%
Diabetes: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Keflex and have Shock?

- Check whether Shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Keflex:

Keflex (15,844 reports)

Shock treatments and more:

Shock (28,534 reports)

Browse all side effects of Keflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shock:

Shock (1,213 drugs)

Browse all the conditions that are associated with Shock:

Shock (1,755 conditions)

Related publications that referenced our studies

Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on cephalexin (the active ingredients of Keflex) and Keflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.