Lacosamide and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Lacosamide (lacosamide), especially for people who are male, 20-29 old, have been taking the drug for 2 - 5 years also take Midazolam, and have Status epilepticus.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Lacosamide. It is created by eHealthMe based on reports of 16,542 people who have side effects when taking Lacosamide from the FDA, and is updated regularly.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,885 drugs and 2,619 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

16,542 people reported to have side effects when taking Lacosamide.
Among them, 59 people (0.36%) have Intestinal obstruction.

Could Lacosamide cause Intestinal obstruction?

Among these 59 people:

How long have people been on Lacosamide when they have Intestinal obstruction? *

What is the gender of people who have Intestinal obstruction when taking Lacosamide? *

female: 17.54 %
male: 82.46 %

What is the age of people who have Intestinal obstruction when taking Lacosamide? *

What are other drugs people take besides Lacosamide? *

What are other side effects people have besides Intestinal obstruction? *

Hypotension (abnormally low blood pressure): 40 people, 67.80%
Fever: 35 people, 59.32%
Drug Ineffective: 28 people, 47.46%
Superinfection: 27 people, 45.76%
Systemic Inflammatory Response Syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection): 27 people, 45.76%
Intestinal Ischaemia (decreased supply of oxygenated blood to the intestines): 27 people, 45.76%
Leukocytosis (increased white blood cells): 26 people, 44.07%
Abdominal Distension: 25 people, 42.37%
Blood Lactic Acid Increased: 24 people, 40.68%
Mucosal Ulceration (ulcers of mucous membrane): 24 people, 40.68%

What are the existing conditions these people have? *

Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 28 people, 47.46%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 26 people, 44.07%
Anaesthesia: 11 people, 18.64%
Sedation: 7 people, 11.86%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 5.08%
High Blood Pressure: 3 people, 5.08%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 5.08%
Cardiac Failure: 3 people, 5.08%
Arterial Occlusive Disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked): 3 people, 5.08%
Pneumonia: 2 people, 3.39%

* Approximation only. Some reports may have incomplete information.

Do you take Lacosamide and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lacosamide:

Lacosamide (16,601 reports)

Browse all side effects of Lacosamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Intestinal obstruction (1,885 drugs)

Browse all the conditions that are associated with Intestinal obstruction:

Intestinal obstruction (2,619 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Lacosamide) and Lacosamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.