Lamictal and Bedwetting - a phase IV clinical study of FDA data

Summary:

Bedwetting is reported as a side effect among people who take Lamictal (lamotrigine), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Bedwetting when taking Lamictal. It is created by eHealthMe based on reports of 74,218 people who have side effects when taking Lamictal from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.

What is Bedwetting?

Bedwetting is found to be associated with 474 drugs and 862 conditions by eHealthMe. Check the latest studies of Bedwetting.



On Jul, 05, 2026

74,218 people reported to have side effects when taking Lamictal.
Among them, 76 people (0.1%) have Bedwetting.

Could Lamictal cause Bedwetting?

Among these 76 people:

How long have people been on Lamictal when they have Bedwetting? *

  • < 1 month: 83.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bedwetting when taking Lamictal? *

  • female: 65.28 %
  • male: 34.72 %

What is the age of people who have Bedwetting when taking Lamictal? *

  • 0-1: 2.22 %
  • 2-9: 13.33 %
  • 10-19: 11.11 %
  • 20-29: 4.44 %
  • 30-39: 22.22 %
  • 40-49: 28.89 %
  • 50-59: 11.11 %
  • 60+: 6.67 %

What are other drugs people take besides Lamictal? *

  1. Xyrem: 28 people, 36.84%
  2. Adderall: 24 people, 31.58%
  3. Nuvigil: 12 people, 15.79%
  4. Provigil: 11 people, 14.47%
  5. Klonopin: 10 people, 13.16%
  6. Lexapro: 9 people, 11.84%
  7. Wellbutrin: 9 people, 11.84%
  8. Vitamin B12: 7 people, 9.21%
  9. Vitamin D3: 7 people, 9.21%
  10. Abilify: 7 people, 9.21%

What are other side effects people have besides Bedwetting? *

  1. Suicidal Ideation: 11 people, 14.47%
  2. High Blood Pressure: 10 people, 13.16%
  3. Nausea And Vomiting: 10 people, 13.16%
  4. Fatigue (feeling of tiredness): 9 people, 11.84%
  5. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 9 people, 11.84%
  6. Stress And Anxiety: 9 people, 11.84%
  7. Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 8 people, 10.53%
  8. Fall: 8 people, 10.53%
  9. Abnormal Behavior: 8 people, 10.53%
  10. Malaise (a feeling of general discomfort or uneasiness): 7 people, 9.21%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 27 people, 35.53%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 17 people, 22.37%
  3. Drowsiness: 11 people, 14.47%
  4. Depression: 6 people, 7.89%
  5. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 4 people, 5.26%
  6. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 3.95%
  7. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 3.95%
  8. Pain: 3 people, 3.95%
  9. Mood Swings (an extreme or rapid change in mood): 2 people, 2.63%
  10. Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 2 people, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Lamictal and have Bedwetting?

- Check whether Bedwetting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamictal:

Bedwetting treatments and more:

How severe was Bedwetting and when was it recovered:

Expand to all the drugs that have ingredients of lamotrigine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamictal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bedwetting:

Browse all the conditions that are associated with Bedwetting:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamictal) and Lamictal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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