Lamictal and Lichen planus - a phase IV clinical study of FDA data

Summary:

Lichen planus is reported as a side effect among people who take Lamictal (lamotrigine), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Lithium Carbonate, and have Bipolar i disorder.

The phase IV clinical study analyzes which people have Lichen planus when taking Lamictal. It is created by eHealthMe based on reports of 74,218 people who have side effects when taking Lamictal from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.

What is Lichen planus?

Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash) is found to be associated with 249 drugs and 557 conditions by eHealthMe. Check the latest studies of Lichen planus.



On Jul, 10, 2026

74,218 people reported to have side effects when taking Lamictal.
Among them, 20 people (0.03%) have Lichen planus.

Could Lamictal cause Lichen planus?

Among these 20 people:

How long have people been on Lamictal when they have Lichen planus? *

  • < 1 month: 45.45 %
  • 1 - 6 months: 18.18 %
  • 6 - 12 months: 27.27 %
  • 1 - 2 years: 9.09 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Lichen planus when taking Lamictal? *

  • female: 78.95 %
  • male: 21.05 %

What is the age of people who have Lichen planus when taking Lamictal? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.88 %
  • 30-39: 0.0 %
  • 40-49: 52.94 %
  • 50-59: 17.65 %
  • 60+: 23.53 %

What are other drugs people take besides Lamictal? *

  1. Famotidine: 5 people, 25.00%
  2. Lithium Carbonate: 5 people, 25.00%
  3. Synthroid: 4 people, 20.00%
  4. Prozac: 4 people, 20.00%
  5. Xanax: 3 people, 15.00%
  6. Polysporin: 3 people, 15.00%
  7. Aspirin: 3 people, 15.00%
  8. Coreg: 3 people, 15.00%
  9. Cozaar: 3 people, 15.00%
  10. Humalog: 3 people, 15.00%

What are other side effects people have besides Lichen planus? *

  1. Urticaria (rash of round, red welts on the skin that itch intensely): 8 people, 40.00%
  2. Rashes (redness): 6 people, 30.00%
  3. Drug Eruption (adverse drug reaction of the skin): 6 people, 30.00%
  4. Skin Erosion (a discontinuity of the skin): 5 people, 25.00%
  5. Skin Swelling: 5 people, 25.00%
  6. Lip Erosion (peeling off of lip): 5 people, 25.00%
  7. Weight Increased: 5 people, 25.00%
  8. Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 5 people, 25.00%
  9. Generalised Erythema (redness of the skin all over the body): 5 people, 25.00%
  10. Fever: 5 people, 25.00%

What are the existing conditions these people have? *

  1. Gastritis (inflammation of stomach): 5 people, 25.00%
  2. Constipation: 5 people, 25.00%
  3. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 5 people, 25.00%
  4. Pain In Extremity: 3 people, 15.00%
  5. Osteoporosis (bones weak and more likely to break): 2 people, 10.00%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 10.00%
  7. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 5.00%
  8. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 5.00%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.00%
  10. Affective Disorder (mental disorder): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lamictal and have Lichen planus?

- Check whether Lichen planus is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamictal:

Lichen planus treatments and more:

How severe was Lichen planus and when was it recovered:

Expand to all the drugs that have ingredients of lamotrigine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamictal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lichen planus:

Browse all the conditions that are associated with Lichen planus:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamictal) and Lamictal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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