Lanirapid and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Lanirapid (metildigoxin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Allopurinol, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Lanirapid. It is created by eHealthMe based on reports of 1,259 people who have side effects when taking Lanirapid from the FDA, and is updated regularly.

What is Lanirapid?

Lanirapid has active ingredients of metildigoxin. eHealthMe is studying from 1,259 Lanirapid users. Check the latest studies of Lanirapid.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,616 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 13, 2026

1,259 people reported to have side effects when taking Lanirapid.
Among them, 12 people (0.95%) have Hypothyroidism.

Among these 12 people:

How long have people been on Lanirapid when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Lanirapid? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Hypothyroidism when taking Lanirapid? *

What are other drugs people take besides Lanirapid? *

Allopurinol: 4 people, 33.33%
Sevelamer Hydrochloride: 3 people, 25.00%
Lasix: 3 people, 25.00%
Rocaltrol: 3 people, 25.00%
Fosamax: 3 people, 25.00%
Tegretol: 3 people, 25.00%
Sunitinib Malate: 2 people, 16.67%
Risperdal: 2 people, 16.67%
Rabeprazole Sodium: 2 people, 16.67%
Fludara: 2 people, 16.67%

What are other side effects people have besides Hypothyroidism? *

Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 4 people, 33.33%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 3 people, 25.00%
Bone Density Decreased: 3 people, 25.00%
Hypothalamo-Pituitary Disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function): 3 people, 25.00%
Osteomalacia (softening of the bones due to a lack of vitamin d): 3 people, 25.00%
Blood Cortisol Increased: 3 people, 25.00%
Blood Corticotrophin Abnormal: 3 people, 25.00%
Back Pain: 3 people, 25.00%
Anastomotic Ulcer: 3 people, 25.00%
Rickets (softening of bones): 3 people, 25.00%

What are the existing conditions these people have? *

Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 3 people, 25.00%
Renal Cell Carcinoma (a kidney cancer): 3 people, 25.00%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 3 people, 25.00%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 3 people, 25.00%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 3 people, 25.00%
Bone Density Decreased: 3 people, 25.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 25.00%
Venous Insufficiency (poor circulation of blood caused by damaged or enlarged veins): 1 person, 8.33%
Splenic Marginal Zone Lymphoma (cancer of the lymph nodes spleen): 1 person, 8.33%
Productive Cough: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Lanirapid and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lanirapid:

Lanirapid (1,259 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,071 reports)

Browse all side effects of Lanirapid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,616 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,600 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on metildigoxin (the active ingredients of Lanirapid) and Lanirapid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.