Lansoprazole and Gastrointestinal toxicity - a phase IV clinical study of FDA data

Summary:

Gastrointestinal toxicity is reported as a side effect among people who take Lansoprazole (lansoprazole), especially for people who are female, 50-59 old, also take Allopurinol, and have Pain.

The phase IV clinical study analyzes which people have Gastrointestinal toxicity when taking Lansoprazole. It is created by eHealthMe based on reports of 128,069 people who have side effects when taking Lansoprazole from the FDA, and is updated regularly.

What is Lansoprazole?

Lansoprazole has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 129,663 Lansoprazole users. Check the latest studies of Lansoprazole.

What is Gastrointestinal toxicity?

Gastrointestinal toxicity (damage to digestive tract by any substance) is found to be associated with 308 drugs and 343 conditions by eHealthMe. Check the latest studies of Gastrointestinal toxicity.

On Aug, 11, 2026

128,069 people reported to have side effects when taking Lansoprazole.
Among them, 12 people (0.01%) have Gastrointestinal toxicity.

Could Lansoprazole cause Gastrointestinal toxicity?

Among these 12 people:

What is the gender of people who have Gastrointestinal toxicity when taking Lansoprazole? *

female: 75 %
male: 25 %

What is the age of people who have Gastrointestinal toxicity when taking Lansoprazole? *

What are other drugs people take besides Lansoprazole? *

What are other side effects people have besides Gastrointestinal toxicity? *

Idiopathic Pneumonia Syndrome (pneumonia-like symptoms): 2 people, 16.67%
Cytomegalovirus Infection: 2 people, 16.67%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 16.67%
Urinary Tract Infection: 2 people, 16.67%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 16.67%
Metapneumovirus Infection (infection with human metapneumovirus): 2 people, 16.67%
Mucosal Inflammation (infection of mucous membrane): 2 people, 16.67%
Pain: 2 people, 16.67%
Periorbital Oedema (swelling around the eyes): 2 people, 16.67%
Pneumonia Cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses): 2 people, 16.67%

What are the existing conditions these people have? *

Toothaches (tooth pain): 3 people, 25.00%
Cough: 3 people, 25.00%
Catheter Site Erythema (redness of skin at catheter site): 3 people, 25.00%
Abdominal Pain Upper: 3 people, 25.00%
Pain: 3 people, 25.00%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 16.67%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 16.67%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 16.67%
Agitation (state of anxiety or nervous excitement): 2 people, 16.67%
Depression: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Lansoprazole and have Gastrointestinal toxicity?

- Check whether Gastrointestinal toxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lansoprazole:

Lansoprazole (129,663 reports)

Browse all side effects of Lansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gastrointestinal toxicity:

Gastrointestinal toxicity (308 drugs)

Browse all the conditions that are associated with Gastrointestinal toxicity:

Gastrointestinal toxicity (343 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lansoprazole (the active ingredients of Lansoprazole) and Lansoprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.