Lansoprazole and Sjogren syndrome - a phase IV clinical study of FDA data

Summary:

Sjogren syndrome is reported as a side effect among people who take Lansoprazole (lansoprazole), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Opdivo, and have Renal cell carcinoma.

The phase IV clinical study analyzes which people have Sjogren syndrome when taking Lansoprazole. It is created by eHealthMe based on reports of 128,069 people who have side effects when taking Lansoprazole from the FDA, and is updated regularly.

What is Lansoprazole?

Lansoprazole has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 129,663 Lansoprazole users. Check the latest studies of Lansoprazole.

What is Sjogren syndrome?

Sjogren syndrome (a disease that causes dryness in the mouth and eyes) is found to be associated with 615 drugs and 968 conditions by eHealthMe. Check the latest studies of Sjogren syndrome.

On Aug, 07, 2026

128,069 people reported to have side effects when taking Lansoprazole.
Among them, 46 people (0.04%) have Sjogren syndrome.

Could Lansoprazole cause Sjogren syndrome?

Among these 46 people:

How long have people been on Lansoprazole when they have Sjogren syndrome? *

What is the gender of people who have Sjogren syndrome when taking Lansoprazole? *

female: 67.44 %
male: 32.56 %

What is the age of people who have Sjogren syndrome when taking Lansoprazole? *

What are other drugs people take besides Lansoprazole? *

What are other side effects people have besides Sjogren syndrome? *

Dry Mouth: 14 people, 30.43%
Joint Pain: 12 people, 26.09%
Rashes (redness): 11 people, 23.91%
Gastroenteritis Staphylococcal (inflammation of stomach and intestine caused by staphylococcal infection): 8 people, 17.39%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 8 people, 17.39%
Sialoadenitis (inflammation of a salivary gland): 8 people, 17.39%
Joint Swelling: 8 people, 17.39%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 17.39%
Colitis (inflammation of colon): 7 people, 15.22%
Dry Eyes (lack of adequate tears): 7 people, 15.22%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 19.57%
Renal Cell Carcinoma (a kidney cancer): 9 people, 19.57%
Diabetes: 7 people, 15.22%
High Blood Cholesterol: 5 people, 10.87%
Ill-Defined Disorder: 4 people, 8.70%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 4.35%
Dizziness: 2 people, 4.35%
Helicobacter Pylori Infection (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 2 people, 4.35%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 4.35%
Prostate Cancer: 2 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Lansoprazole and have Sjogren syndrome?

- Check whether Sjogren syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lansoprazole:

Lansoprazole (129,663 reports)

Sjogren syndrome treatments and more:

Sjogren syndrome (12,489 reports)

Browse all side effects of Lansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sjogren syndrome:

Sjogren syndrome (615 drugs)

Browse all the conditions that are associated with Sjogren syndrome:

Sjogren syndrome (968 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lansoprazole (the active ingredients of Lansoprazole) and Lansoprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.