Lansoprazole and Systolic dysfunction - a phase IV clinical study of FDA data

Summary:

Systolic dysfunction is reported as a side effect among people who take Lansoprazole (lansoprazole), especially for people who are female, 60+ old, also take Ondansetron, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Systolic dysfunction when taking Lansoprazole. It is created by eHealthMe based on reports of 128,069 people who have side effects when taking Lansoprazole from the FDA, and is updated regularly.

What is Lansoprazole?

Lansoprazole has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 129,663 Lansoprazole users. Check the latest studies of Lansoprazole.

What is Systolic dysfunction?

Systolic dysfunction (impaired ventricular contraction) is found to be associated with 200 drugs and 220 conditions by eHealthMe. Check the latest studies of Systolic dysfunction.

On Aug, 11, 2026

128,069 people reported to have side effects when taking Lansoprazole.
Among them, 14 people (0.01%) have Systolic dysfunction.

Could Lansoprazole cause Systolic dysfunction?

Among these 14 people:

What is the gender of people who have Systolic dysfunction when taking Lansoprazole? *

female: 75 %
male: 25 %

What is the age of people who have Systolic dysfunction when taking Lansoprazole? *

What are other drugs people take besides Lansoprazole? *

Ondansetron: 5 people, 35.71%
Vancomycin: 4 people, 28.57%
Zopiclone: 3 people, 21.43%
Piperacillin And Tazobactam: 3 people, 21.43%
Amlodipine: 3 people, 21.43%
Codeine: 3 people, 21.43%
Ursodeoxycholic Acid: 3 people, 21.43%
Insulin: 3 people, 21.43%
Tamiflu: 3 people, 21.43%
Cefazolin: 2 people, 14.29%

What are other side effects people have besides Systolic dysfunction? *

Heart Palpitations (feelings or sensations that your heart is pounding or racing): 9 people, 64.29%
Fatigue (feeling of tiredness): 9 people, 64.29%
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery): 8 people, 57.14%
Dyspnea At Rest: 8 people, 57.14%
Pleural Effusion (water on the lungs): 8 people, 57.14%
Conjunctival Haemorrhage (bleeding underneath the conjunctiva): 8 people, 57.14%
Paleness (unusual lightness of skin colour): 8 people, 57.14%
Oedema Peripheral (superficial swelling): 8 people, 57.14%
Normochromic Normocytic Anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits): 8 people, 57.14%
Crepitations (noises are produced by the rubbing of parts one against the other): 8 people, 57.14%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 21.43%
Constipation: 2 people, 14.29%
Urinary Tract Infection: 2 people, 14.29%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 7.14%
Breast Cancer: 1 person, 7.14%
Breast Cancer Metastatic: 1 person, 7.14%
Cough: 1 person, 7.14%
Diarrhea: 1 person, 7.14%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 7.14%
Fever: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Lansoprazole and have Systolic dysfunction?

- Check whether Systolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lansoprazole:

Lansoprazole (129,663 reports)

Browse all side effects of Lansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systolic dysfunction:

Systolic dysfunction (200 drugs)

Browse all the conditions that are associated with Systolic dysfunction:

Systolic dysfunction (220 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lansoprazole (the active ingredients of Lansoprazole) and Lansoprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.