Lantus and Hepatic function abnormal - a phase IV clinical study of FDA data

Summary:

Hepatic function abnormal is reported as a side effect among people who take Lantus (insulin glargine recombinant), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Humalog, and have High blood pressure.

The phase IV clinical study analyzes which people have Hepatic function abnormal when taking Lantus. It is created by eHealthMe based on reports of 190,478 people who have side effects when taking Lantus from the FDA, and is updated regularly.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,781 Lantus users. Check the latest studies of Lantus.

What is Hepatic function abnormal?

Hepatic function abnormal is found to be associated with 1,487 drugs and 2,010 conditions by eHealthMe. Check the latest studies of Hepatic function abnormal.

On Nov, 02, 2025

190,478 people reported to have side effects when taking Lantus.
Among them, 288 people (0.15%) have Hepatic function abnormal.

Could Lantus cause Hepatic function abnormal?

Among these 288 people:

How long have people been on Lantus when they have Hepatic function abnormal? *

What is the gender of people who have Hepatic function abnormal when taking Lantus? *

female: 40.79 %
male: 59.21 %

What is the age of people who have Hepatic function abnormal when taking Lantus? *

What are other drugs people take besides Lantus? *

What are other side effects people have besides Hepatic function abnormal? *

Aspartate Aminotransferase Increased: 69 people, 23.96%
Alanine Aminotransferase Increased: 68 people, 23.61%
Renal Impairment (severely reduced kidney function): 34 people, 11.81%
Gamma-Glutamyltransferase Increased: 27 people, 9.38%
Fever: 24 people, 8.33%
Blood Alkaline Phosphatase Increased: 21 people, 7.29%
Blood Lactate Dehydrogenase Increased: 15 people, 5.21%
Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 15 people, 5.21%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 12 people, 4.17%
Blood Glucose Increased: 12 people, 4.17%

What are the existing conditions these people have? *

High Blood Pressure: 44 people, 15.28%
Hyperlipidaemia (presence of excess lipids in the blood): 18 people, 6.25%
Pain: 11 people, 3.82%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 3.47%
Dyslipidaemia (abnormal amount of lipids): 10 people, 3.47%
Insomnia (sleeplessness): 10 people, 3.47%
Constipation: 10 people, 3.47%
Depression: 9 people, 3.12%
Stable Angina (a constant chest pain): 8 people, 2.78%
Prostate Cancer: 8 people, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Lantus and have Hepatic function abnormal?

- Check whether Hepatic function abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lantus:

Lantus (191,781 reports)

Common Lantus side effects:

Browse all side effects of Lantus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Hepatic function abnormal:

Browse all the drugs that are associated with Hepatic function abnormal:

Hepatic function abnormal (1,487 drugs)

Common conditions associated with Hepatic function abnormal:

Hypertension: 2,738 reports
Rheumatoid arthritis: 1,426 reports
Cancer - kidney: 1,400 reports
Preventive health care: 1,380 reports
Non-small cell lung cancer: 1,251 reports
Breast cancer: 1,019 reports
Constipation: 971 reports
Sleeping: 966 reports
Hyperlipidaemia: 949 reports
Dm: 940 reports

Browse all the conditions that are associated with Hepatic function abnormal:

Hepatic function abnormal (2,010 conditions)

Drugs similar to Lantus and Hepatic function abnormal :

How the study uses the data?

The study uses data from the FDA. It is based on insulin glargine recombinant (the active ingredients of Lantus) and Lantus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.