Levaquin and Multiple sclerosis relapse - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis relapse is reported as a side effect among people who take Levaquin (levofloxacin), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Tysabri, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Multiple sclerosis relapse when taking Levaquin. It is created by eHealthMe based on reports of 54,998 people who have side effects when taking Levaquin from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Multiple sclerosis relapse?

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,030 drugs and 943 conditions by eHealthMe. Check the latest studies of Multiple sclerosis relapse.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

54,998 people reported to have side effects when taking Levaquin.
Among them, 88 people (0.16%) have Multiple sclerosis relapse.

Could Levaquin cause Multiple sclerosis relapse?

Among these 88 people:

How long have people been on Levaquin when they have Multiple sclerosis relapse? *

What is the gender of people who have Multiple sclerosis relapse when taking Levaquin? *

female: 87.21 %
male: 12.79 %

What is the age of people who have Multiple sclerosis relapse when taking Levaquin? *

What are other drugs people take besides Levaquin? *

What are other side effects people have besides Multiple sclerosis relapse? *

Urinary Tract Infection: 22 people, 25.00%
Weakness: 18 people, 20.45%
Gait Disturbance: 16 people, 18.18%
Fall: 14 people, 15.91%
Muscle Spasms (muscle contraction): 13 people, 14.77%
Fatigue (feeling of tiredness): 13 people, 14.77%
Kidney Infection: 12 people, 13.64%
Abdominal Pain: 10 people, 11.36%
Depression: 10 people, 11.36%
Hypoaesthesia (reduced sense of touch or sensation): 10 people, 11.36%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 68 people, 77.27%
Gait Disturbance: 10 people, 11.36%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 10 people, 11.36%
Pain: 9 people, 10.23%
Immunodeficiency Common Variable: 9 people, 10.23%
Depression: 8 people, 9.09%
Constipation: 7 people, 7.95%
Sleep Disorder: 7 people, 7.95%
High Blood Pressure: 7 people, 7.95%
Hypersensitivity: 6 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Levaquin and have Multiple sclerosis relapse?

- Check whether Multiple sclerosis relapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levaquin:

Levaquin (56,638 reports)

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis relapse:

Multiple sclerosis relapse (1,030 drugs)

Browse all the conditions that are associated with Multiple sclerosis relapse:

Multiple sclerosis relapse (943 conditions)

Related publications that referenced our studies

Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on levofloxacin (the active ingredients of Levaquin) and Levaquin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.