Levothyroxine sodium and Hypoglycaemic coma - a phase IV clinical study of FDA data

Summary:

Hypoglycaemic coma is reported as a side effect among people who take Levothyroxine sodium (levothyroxine sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lantus, and have Type 1 diabetes.

The phase IV clinical study analyzes which people have Hypoglycaemic coma when taking Levothyroxine sodium. It is created by eHealthMe based on reports of 122,907 people who have side effects when taking Levothyroxine sodium from the FDA, and is updated regularly.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,812 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

What is Hypoglycaemic coma?

Hypoglycaemic coma (coma due to deficiency of glucose in the bloodstream) is found to be associated with 235 drugs and 367 conditions by eHealthMe. Check the latest studies of Hypoglycaemic coma.



On Jul, 05, 2026

122,907 people reported to have side effects when taking Levothyroxine sodium.
Among them, 44 people (0.04%) have Hypoglycaemic coma.

Could Levothyroxine sodium cause Hypoglycaemic coma?

Among these 44 people:

How long have people been on Levothyroxine sodium when they have Hypoglycaemic coma? *

  • < 1 month: 40 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 20 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 40 %

What is the gender of people who have Hypoglycaemic coma when taking Levothyroxine sodium? *

  • female: 69.77 %
  • male: 30.23 %

What is the age of people who have Hypoglycaemic coma when taking Levothyroxine sodium? *

  • 0-1: 0.0 %
  • 2-9: 2.38 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.76 %
  • 40-49: 19.05 %
  • 50-59: 21.43 %
  • 60+: 52.38 %

What are other drugs people take besides Levothyroxine sodium? *

  1. Lantus: 15 people, 34.09%
  2. Furosemide: 9 people, 20.45%
  3. Glimepiride: 5 people, 11.36%
  4. Spironolactone: 4 people, 9.09%
  5. Metformin: 4 people, 9.09%
  6. Isoptin: 4 people, 9.09%
  7. Humalog: 4 people, 9.09%
  8. Simvastatin: 4 people, 9.09%
  9. Morphine: 4 people, 9.09%
  10. Cordarone: 4 people, 9.09%

What are other side effects people have besides Hypoglycaemic coma? *

  1. Lactic Acidosis (low ph in body tissues): 4 people, 9.09%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 9.09%
  3. Blood Glucose Increased: 3 people, 6.82%
  4. Hypoglycemia (low blood sugar): 3 people, 6.82%
  5. Circulatory Collapse: 3 people, 6.82%
  6. Blood Glucose Decreased: 3 people, 6.82%
  7. Blood Alkaline Phosphatase Increased: 2 people, 4.55%
  8. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 2 people, 4.55%
  9. Overdose: 2 people, 4.55%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 4.55%

What are the existing conditions these people have? *

  1. Type 1 Diabetes: 9 people, 20.45%
  2. Diabetes: 6 people, 13.64%
  3. Type 2 Diabetes: 5 people, 11.36%
  4. Pneumonia: 3 people, 6.82%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.82%
  6. Urinary Tract Infection: 2 people, 4.55%
  7. Hypersensitivity: 2 people, 4.55%
  8. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 2 people, 4.55%
  9. Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 4.55%
  10. Depression: 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Levothyroxine sodium and have Hypoglycaemic coma?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levothyroxine sodium:

Hypoglycaemic coma treatments and more:

How severe was Hypoglycaemic coma and when was it recovered:

Expand to all the drugs that have ingredients of levothyroxine sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levothyroxine sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoglycaemic coma:

Browse all the conditions that are associated with Hypoglycaemic coma:


How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothyroxine sodium) and Levothyroxine sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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