Linaclotide and Dysphagia aggravated - a phase IV clinical study of FDA data

Summary:

Dysphagia aggravated is reported as a side effect among people who take Linaclotide (linaclotide), especially for people who are female, 60+ old, also take Botox, and have Crohn's disease.

The phase IV clinical study analyzes which people have Dysphagia aggravated when taking Linaclotide. It is created by eHealthMe based on reports of 2,196 people who have side effects when taking Linaclotide from the FDA, and is updated regularly.

What is Linaclotide?

Linaclotide has active ingredients of linaclotide. eHealthMe is studying from 2,197 Linaclotide users. Check the latest studies of Linaclotide.

What is Dysphagia aggravated?

Dysphagia aggravated (serious condition in which swallowing is difficult or painful) is found to be associated with 1,719 drugs and 586 conditions by eHealthMe. Check the latest studies of Dysphagia aggravated.

On Jul, 13, 2026

2,196 people reported to have side effects when taking Linaclotide.
Among them, 23 people (1.05%) have Dysphagia aggravated.

Could Linaclotide cause Dysphagia aggravated?

Among these 23 people:

What is the gender of people who have Dysphagia aggravated when taking Linaclotide? *

female: 78.95 %
male: 21.05 %

What is the age of people who have Dysphagia aggravated when taking Linaclotide? *

What are other drugs people take besides Linaclotide? *

Acetaminophen: 4 people, 17.39%
Botox: 4 people, 17.39%
Polyethylene Glycol 3350: 3 people, 13.04%
Mycophenolate Mofetil: 3 people, 13.04%
Rabeprazole Sodium: 3 people, 13.04%
Risedronate Sodium: 3 people, 13.04%
Methylprednisolone: 3 people, 13.04%
Diphenhydramine Hydrochloride: 3 people, 13.04%
Benadryl: 3 people, 13.04%
Prednisone: 3 people, 13.04%

What are other side effects people have besides Dysphagia aggravated? *

Weakness: 8 people, 34.78%
Fatigue (feeling of tiredness): 7 people, 30.43%
Constipation: 7 people, 30.43%
Abdominal Pain: 6 people, 26.09%
Dyspnea (difficult or laboured breathing): 6 people, 26.09%
Abdominal Pain Upper: 6 people, 26.09%
Stress And Anxiety: 5 people, 21.74%
Nausea (feeling of having an urge to vomit): 5 people, 21.74%
Headache (pain in head): 5 people, 21.74%
Rashes (redness): 4 people, 17.39%

What are the existing conditions these people have? *

Constipation: 4 people, 17.39%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 17.39%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 3 people, 13.04%
Oesophageal Spasm (contraction of oesophagus): 2 people, 8.70%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 8.70%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 8.70%
Weight Decreased: 1 person, 4.35%
Depression: 1 person, 4.35%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 4.35%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Linaclotide and have Dysphagia aggravated?

- Check whether Dysphagia aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Linaclotide:

Linaclotide (2,197 reports)

Browse all side effects of Linaclotide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dysphagia aggravated:

Dysphagia aggravated (1,719 drugs)

Browse all the conditions that are associated with Dysphagia aggravated:

Dysphagia aggravated (586 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on linaclotide (the active ingredients of Linaclotide) and Linaclotide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.