Lioresal and Rickets - a phase IV clinical study of FDA data

Summary:

Rickets is reported as a side effect among people who take Lioresal (baclofen), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Vitamin B12, and have Pain.

The phase IV clinical study analyzes which people have Rickets when taking Lioresal. It is created by eHealthMe based on reports of 20,521 people who have side effects when taking Lioresal from the FDA, and is updated regularly.

What is Lioresal?

Lioresal has active ingredients of baclofen. It is often used in multiple sclerosis. eHealthMe is studying from 20,572 Lioresal users. Check the latest studies of Lioresal.

What is Rickets?

Rickets (softening of bones) is found to be associated with 1,086 drugs and 1,460 conditions by eHealthMe. Check the latest studies of Rickets.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

20,521 people reported to have side effects when taking Lioresal.
Among them, 28 people (0.14%) have Rickets.

Could Lioresal cause Rickets?

Among these 28 people:

How long have people been on Lioresal when they have Rickets? *

  • < 1 month: 20 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 60 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Rickets when taking Lioresal? *

  • female: 88.89 %
  • male: 11.11 %

What is the age of people who have Rickets when taking Lioresal? *

  • 0-1: 4.76 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 14.29 %
  • 50-59: 52.38 %
  • 60+: 14.29 %

What are other drugs people take besides Lioresal? *

  1. Vitamin B12: 11 people, 39.29%
  2. Klonopin: 10 people, 35.71%
  3. Lipitor: 9 people, 32.14%
  4. Gilenya: 9 people, 32.14%
  5. Zofran: 8 people, 28.57%
  6. Colace: 8 people, 28.57%
  7. Tylenol: 8 people, 28.57%
  8. Miralax: 8 people, 28.57%
  9. Estrace: 8 people, 28.57%
  10. Gaviscon: 6 people, 21.43%

What are other side effects people have besides Rickets? *

  1. Pain: 11 people, 39.29%
  2. Depression: 10 people, 35.71%
  3. Speech Impairment (Adult) (inability to speak (adult)): 9 people, 32.14%
  4. High Blood Pressure: 9 people, 32.14%
  5. Essential Hypertension (primary hypertension): 8 people, 28.57%
  6. Nausea (feeling of having an urge to vomit): 8 people, 28.57%
  7. Nausea And Vomiting: 8 people, 28.57%
  8. Weight Loss: 7 people, 25.00%
  9. Swallowing Difficulty: 7 people, 25.00%
  10. Sleep Apnea Syndrome: 7 people, 25.00%

What are the existing conditions these people have? *

  1. Pain: 7 people, 25.00%
  2. Thermal Burn (burn by heat): 6 people, 21.43%
  3. Itching: 6 people, 21.43%
  4. Nausea (feeling of having an urge to vomit): 6 people, 21.43%
  5. Sleep Disorder: 4 people, 14.29%
  6. Hypersensitivity: 4 people, 14.29%
  7. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 14.29%
  8. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 3 people, 10.71%
  9. Muscle Spasms (muscle contraction): 3 people, 10.71%
  10. Type 2 Diabetes: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Lioresal and have Rickets?

- Check whether Rickets is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lioresal:

Rickets treatments and more:

How severe was Rickets and when was it recovered:

Expand to all the drugs that have ingredients of baclofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lioresal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rickets:

Browse all the conditions that are associated with Rickets:


How the study uses the data?

The study uses data from the FDA. It is based on baclofen (the active ingredients of Lioresal) and Lioresal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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