Lopurin and Brain abscess - a phase IV clinical study of FDA data

Summary:

Brain abscess is reported as a side effect among people who take Lopurin (allopurinol), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Pradaxa, and have Gastritis.

The phase IV clinical study analyzes which people have Brain abscess when taking Lopurin. It is created by eHealthMe based on reports of 188,140 people who have side effects when taking Lopurin from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Brain abscess?

Brain abscess is found to be associated with 223 drugs and 626 conditions by eHealthMe. Check the latest studies of Brain abscess.

On Aug, 06, 2026

188,140 people reported to have side effects when taking Lopurin.
Among them, 32 people (0.02%) have Brain abscess.

Among these 32 people:

How long have people been on Lopurin when they have Brain abscess? *

What is the gender of people who have Brain abscess when taking Lopurin? *

female: 48.28 %
male: 51.72 %

What is the age of people who have Brain abscess when taking Lopurin? *

What are other drugs people take besides Lopurin? *

What are other side effects people have besides Brain abscess? *

Cerebral Ischaemia (insufficient blood flow to the brain to meet metabolic demand): 10 people, 31.25%
Cerebral Haemorrhage (bleeding within the brain): 7 people, 21.88%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 7 people, 21.88%
Staphylococcal Infection (an infection with staphylococcus bacteria): 7 people, 21.88%
Hemiparesis (weakness on one side of the body): 6 people, 18.75%
Brain Herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull): 6 people, 18.75%
Metabolic Syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease): 5 people, 15.62%
Quality Of Life Decreased: 5 people, 15.62%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 5 people, 15.62%
Cardiac Disorder: 5 people, 15.62%

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 9 people, 28.12%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 28.12%
Gastritis (inflammation of stomach): 9 people, 28.12%
Essential Hypertension (primary hypertension): 5 people, 15.62%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 12.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 12.50%
High Blood Pressure: 4 people, 12.50%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 9.38%
Pain: 2 people, 6.25%
Nausea (feeling of having an urge to vomit): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and have Brain abscess?

- Check whether Brain abscess is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopurin:

Lopurin (190,798 reports)

Brain abscess treatments and more:

Brain abscess (3,459 reports)

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain abscess:

Brain abscess (223 drugs)

Browse all the conditions that are associated with Brain abscess:

Brain abscess (626 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Lopurin) and Lopurin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.