Lortab and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Lortab (acetaminophen; hydrocodone bitartrate), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Lasix, and have Cardiac disorder.

The phase IV clinical study analyzes which people have Cachexia when taking Lortab. It is created by eHealthMe based on reports of 29,547 people who have side effects when taking Lortab from the FDA, and is updated regularly.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 735 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Cachexia.

On Oct, 20, 2025

29,547 people reported to have side effects when taking Lortab.
Among them, 32 people (0.11%) have Cachexia.

Among these 32 people:

How long have people been on Lortab when they have Cachexia? *

What is the gender of people who have Cachexia when taking Lortab? *

female: 65.62 %
male: 34.38 %

What is the age of people who have Cachexia when taking Lortab? *

What are other drugs people take besides Lortab? *

What are other side effects people have besides Cachexia? *

Weight Decreased: 16 people, 50.00%
Weakness: 14 people, 43.75%
Nausea (feeling of having an urge to vomit): 14 people, 43.75%
Dehydration (dryness resulting from the removal of water): 11 people, 34.38%
Nausea And Vomiting: 11 people, 34.38%
Cardiac Failure Congestive: 10 people, 31.25%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 10 people, 31.25%
Fatigue (feeling of tiredness): 9 people, 28.12%
Diarrhea: 9 people, 28.12%
Pneumonia: 8 people, 25.00%

What are the existing conditions these people have? *

Pancreatic Carcinoma (pancreatic cancer): 2 people, 6.25%
Nausea And Vomiting: 2 people, 6.25%
Nausea (feeling of having an urge to vomit): 2 people, 6.25%
Bladder Cancer: 2 people, 6.25%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 6.25%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 2 people, 6.25%
Cardiac Disorder: 2 people, 6.25%
Prostate Cancer: 1 person, 3.12%
Constipation: 1 person, 3.12%
Breast Cancer: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Lortab and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lortab:

Lortab (31,285 reports)

Cachexia treatments and more:

Cachexia (7,763 reports)

How severe was Cachexia and when was it recovered:

Cachexia in Lortab

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Cachexia and drugs with ingredients of acetaminophen; hydrocodone bitartrate (226 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lortab:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Cachexia (735 drugs)

Browse all the conditions that are associated with Cachexia:

Cachexia (1,194 conditions)

Drugs similar to Lortab and Cachexia :

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Lortab) and Lortab (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.