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Ibuprofen and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Augmentin, and have Bladder pain.

The phase IV clinical study analyzes which people have Cachexia when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,256 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 733 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Cachexia.

On Oct, 25, 2025

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 121 people (0.05%) have Cachexia.

Could Ibuprofen cause Cachexia?

Among these 121 people:

How long have people been on Ibuprofen when they have Cachexia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cachexia when taking Ibuprofen? *

  • female: 60.18 %
  • male: 39.82 %

What is the age of people who have Cachexia when taking Ibuprofen? *

  • 0-1: 0.0 %
  • 2-9: 0.98 %
  • 10-19: 1.96 %
  • 20-29: 1.96 %
  • 30-39: 6.86 %
  • 40-49: 24.51 %
  • 50-59: 29.41 %
  • 60+: 34.31 %

What are other drugs people take besides Ibuprofen? *

  1. Oxycontin: 25 people, 20.66%
  2. Augmentin: 25 people, 20.66%
  3. Pregabalin: 23 people, 19.01%
  4. Fentanyl: 22 people, 18.18%
  5. Dexamethasone: 22 people, 18.18%
  6. Torsemide: 22 people, 18.18%
  7. Apixaban: 22 people, 18.18%
  8. Metoclopramide: 21 people, 17.36%
  9. Prednisone: 15 people, 12.40%
  10. Pantoprazole: 13 people, 10.74%

What are other side effects people have besides Cachexia? *

  1. Weakness: 57 people, 47.11%
  2. Weight Decreased: 56 people, 46.28%
  3. Nausea (feeling of having an urge to vomit): 56 people, 46.28%
  4. Fatigue (feeling of tiredness): 55 people, 45.45%
  5. Dyspnea (difficult or laboured breathing): 51 people, 42.15%
  6. Nausea And Vomiting: 47 people, 38.84%
  7. Joint Pain: 44 people, 36.36%
  8. Fall: 41 people, 33.88%
  9. Rashes (redness): 39 people, 32.23%
  10. Confusion: 38 people, 31.40%

What are the existing conditions these people have? *

  1. Bladder Pain: 25 people, 20.66%
  2. Urinary Tract Infection: 13 people, 10.74%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 9.92%
  4. Joint Pain: 11 people, 9.09%
  5. Migraine (headache): 9 people, 7.44%
  6. Hypersensitivity: 9 people, 7.44%
  7. Facial Pain: 8 people, 6.61%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 4.96%
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 4.13%
  10. Osteoporosis (bones weak and more likely to break): 4 people, 3.31%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Cachexia treatments and more:

How severe was Cachexia and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Ibuprofen side effects:

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Cachexia:

Browse all the drugs that are associated with Cachexia:

Common conditions associated with Cachexia:

Browse all the conditions that are associated with Cachexia:

Drugs similar to Ibuprofen and Cachexia :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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