Lupron and Precocious puberty - a phase IV clinical study of FDA data

Summary:

Precocious puberty is reported as a side effect among people who take Lupron (leuprolide acetate), especially for people who are female, 2-9 old, have been taking the drug for 6 - 12 months also take Benadryl, and have Body height below normal.

The phase IV clinical study analyzes which people have Precocious puberty when taking Lupron. It is created by eHealthMe based on reports of 41,483 people who have side effects when taking Lupron from the FDA, and is updated regularly.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.

What is Precocious puberty?

Precocious puberty is found to be associated with 41 drugs and 171 conditions by eHealthMe. Check the latest studies of Precocious puberty.

On Jul, 05, 2026

41,483 people reported to have side effects when taking Lupron.
Among them, 24 people (0.06%) have Precocious puberty.

Among these 24 people:

How long have people been on Lupron when they have Precocious puberty? *

What is the gender of people who have Precocious puberty when taking Lupron? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Precocious puberty when taking Lupron? *

What are other drugs people take besides Lupron? *

What are other side effects people have besides Precocious puberty? *

Blood Luteinising Hormone Abnormal: 4 people, 16.67%
Hair Growth Abnormal: 3 people, 12.50%
Drug Ineffective: 3 people, 12.50%
Hoarseness Or Changing Voice: 2 people, 8.33%
Injection Site Pain: 2 people, 8.33%
Nausea And Vomiting: 2 people, 8.33%
Growth Retardation (delayed growth): 1 person, 4.17%
Growth Accelerated (growth more than expected): 1 person, 4.17%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 1 person, 4.17%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1 person, 4.17%

What are the existing conditions these people have? *

Stress And Anxiety: 1 person, 4.17%
Small For Dates Baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age): 1 person, 4.17%
Postpartum Depression (depression suffered by a mother following childbirth): 1 person, 4.17%
Muscle Spasms (muscle contraction): 1 person, 4.17%
Growth Hormone Deficiency: 1 person, 4.17%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.17%
Body Height Below Normal: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Lupron and have Precocious puberty?

- Check whether Precocious puberty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lupron:

Lupron (42,122 reports)

Browse all side effects of Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Precocious puberty:

Precocious puberty (41 drugs)

Browse all the conditions that are associated with Precocious puberty:

Precocious puberty (171 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate (the active ingredients of Lupron) and Lupron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.