Lupron and Resorption bone increased - a phase IV clinical study of FDA data

Summary:

Resorption bone increased is reported as a side effect among people who take Lupron (leuprolide acetate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Resorption bone increased when taking Lupron. It is created by eHealthMe based on reports of 41,483 people who have side effects when taking Lupron from the FDA, and is updated regularly.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.

What is Resorption bone increased?

Resorption bone increased is found to be associated with 236 drugs and 262 conditions by eHealthMe. Check the latest studies of Resorption bone increased.

On Jul, 14, 2026

41,483 people reported to have side effects when taking Lupron.
Among them, 19 people (0.05%) have Resorption bone increased.

Could Lupron cause Resorption bone increased?

Among these 19 people:

How long have people been on Lupron when they have Resorption bone increased? *

What is the gender of people who have Resorption bone increased when taking Lupron? *

female: 31.58 %
male: 68.42 %

What is the age of people who have Resorption bone increased when taking Lupron? *

What are other drugs people take besides Lupron? *

What are other side effects people have besides Resorption bone increased? *

Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 11 people, 57.89%
Osteolysis (dissolution of bone): 9 people, 47.37%
Periodontitis (inflammation of the tissue around the teeth): 9 people, 47.37%
Loose Tooth: 9 people, 47.37%
Primary Sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 9 people, 47.37%
Stress And Anxiety: 8 people, 42.11%
Pain: 8 people, 42.11%
Injury: 7 people, 36.84%
Osteomyelitis (infection of bone): 7 people, 36.84%
Deformity (disfigurement): 7 people, 36.84%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 9 people, 47.37%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 21.05%
Osteoporosis (bones weak and more likely to break): 3 people, 15.79%
High Blood Pressure: 1 person, 5.26%
Gastric Ulcer (stomach ulcer): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Lupron and have Resorption bone increased?

- Check whether Resorption bone increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lupron:

Lupron (42,122 reports)

Browse all side effects of Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Resorption bone increased:

Resorption bone increased (236 drugs)

Browse all the conditions that are associated with Resorption bone increased:

Resorption bone increased (262 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate (the active ingredients of Lupron) and Lupron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.