Luvox and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Luvox (fluvoxamine maleate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lithium Carbonate, and have Constipation.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Luvox. It is created by eHealthMe based on reports of 12,486 people who have side effects when taking Luvox from the FDA, and is updated regularly.

What is Luvox?

Luvox has active ingredients of fluvoxamine maleate. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 13,438 Luvox users. Check the latest studies of Luvox.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,232 drugs and 836 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Oct, 27, 2025

12,486 people reported to have side effects when taking Luvox.
Among them, 12 people (0.1%) have Sinus node dysfunction.

Could Luvox cause Sinus node dysfunction?

Among these 12 people:

How long have people been on Luvox when they have Sinus node dysfunction? *

What is the gender of people who have Sinus node dysfunction when taking Luvox? *

female: 100 %
male: 0.0 %

What is the age of people who have Sinus node dysfunction when taking Luvox? *

What are other drugs people take besides Luvox? *

What are other side effects people have besides Sinus node dysfunction? *

Hypotension (abnormally low blood pressure): 4 people, 33.33%
Atrioventricular Block (heart block): 3 people, 25.00%
Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 2 people, 16.67%
Nausea (feeling of having an urge to vomit): 2 people, 16.67%
Kleptomania (the urge to steal items for reasons other than personal use or financial gain): 2 people, 16.67%
Weakness: 1 person, 8.33%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 8.33%
Atrioventricular Block Second Degree (heart block second degree): 1 person, 8.33%
Balance Disorder: 1 person, 8.33%
Cardiac Output Decreased: 1 person, 8.33%

What are the existing conditions these people have? *

Constipation: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Luvox and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Luvox:

Luvox (13,438 reports)

Browse all side effects of Luvox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus node dysfunction:

Sinus node dysfunction (1,232 drugs)

Browse all the conditions that are associated with Sinus node dysfunction:

Sinus node dysfunction (836 conditions)

Drugs similar to Luvox and Sinus node dysfunction :

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on fluvoxamine maleate (the active ingredients of Luvox) and Luvox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.