Lyrica and Hypercoagulation - a phase IV clinical study of FDA data

Summary:

Hypercoagulation is reported as a side effect among people who take Lyrica (pregabalin), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Coumadin, and have Oedema.

The phase IV clinical study analyzes which people have Hypercoagulation when taking Lyrica. It is created by eHealthMe based on reports of 255,839 people who have side effects when taking Lyrica from the FDA, and is updated regularly.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.

What is Hypercoagulation?

Hypercoagulation (increased tendency for clotting of the blood) is found to be associated with 380 drugs and 538 conditions by eHealthMe. Check the latest studies of Hypercoagulation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

255,839 people reported to have side effects when taking Lyrica.
Among them, 37 people (0.01%) have Hypercoagulation.

Among these 37 people:

How long have people been on Lyrica when they have Hypercoagulation? *

What is the gender of people who have Hypercoagulation when taking Lyrica? *

female: 86.49 %
male: 13.51 %

What is the age of people who have Hypercoagulation when taking Lyrica? *

What are other drugs people take besides Lyrica? *

What are other side effects people have besides Hypercoagulation? *

Stress And Anxiety: 25 people, 67.57%
Insomnia (sleeplessness): 20 people, 54.05%
Infection: 19 people, 51.35%
Depression: 19 people, 51.35%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 19 people, 51.35%
Abdominal Pain: 18 people, 48.65%
Joint Pain: 18 people, 48.65%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 16 people, 43.24%
Spinal Osteoarthritis (joint cartilage loss in spine): 16 people, 43.24%
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 15 people, 40.54%

What are the existing conditions these people have? *

Hypomania (a mild form of mania, marked by elation and hyperactivity): 11 people, 29.73%
Oedema (fluid collection in tissue): 11 people, 29.73%
Birth Control: 4 people, 10.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 10.81%
Breast Cancer: 4 people, 10.81%
Protein S Deficiency: 4 people, 10.81%
Pancreatic Carcinoma (pancreatic cancer): 4 people, 10.81%
Nausea (feeling of having an urge to vomit): 4 people, 10.81%
Benign Bone Neoplasm (benign (non-cancerous) tumours of the bone): 3 people, 8.11%
Stress And Anxiety: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Lyrica and have Hypercoagulation?

- Check whether Hypercoagulation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lyrica:

Lyrica (261,646 reports)

Browse all side effects of Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercoagulation:

Hypercoagulation (380 drugs)

Browse all the conditions that are associated with Hypercoagulation:

Hypercoagulation (538 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Lyrica) and Lyrica (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.