Lyrica and Obstructive uropathy - a phase IV clinical study of FDA data

Summary:

Obstructive uropathy is reported as a side effect among people who take Lyrica (pregabalin), especially for people who are male, 60+ old, also take Cymbalta, and have Osteoporosis.

The phase IV clinical study analyzes which people have Obstructive uropathy when taking Lyrica. It is created by eHealthMe based on reports of 255,839 people who have side effects when taking Lyrica from the FDA, and is updated regularly.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.

What is Obstructive uropathy?

Obstructive uropathy (a blockage that prevents urine from leaving your kidneys) is found to be associated with 148 drugs and 465 conditions by eHealthMe. Check the latest studies of Obstructive uropathy.

On Jul, 22, 2026

255,839 people reported to have side effects when taking Lyrica.
Among them, 26 people (0.01%) have Obstructive uropathy.

Could Lyrica cause Obstructive uropathy?

Among these 26 people:

What is the gender of people who have Obstructive uropathy when taking Lyrica? *

female: 50 %
male: 50 %

What is the age of people who have Obstructive uropathy when taking Lyrica? *

What are other drugs people take besides Lyrica? *

What are other side effects people have besides Obstructive uropathy? *

Urination - Painful: 23 people, 88.46%
Back Pain: 23 people, 88.46%
Kidney Stones: 23 people, 88.46%
Bone Pain: 22 people, 84.62%
Osteomyelitis (infection of bone): 22 people, 84.62%
Infection: 22 people, 84.62%
Abdominal Pain: 21 people, 80.77%
Osteonecrosis Of Jaw (death of bone of jaw): 21 people, 80.77%
Nausea (feeling of having an urge to vomit): 20 people, 76.92%
Fall: 20 people, 76.92%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 22 people, 84.62%
Prostate Cancer: 11 people, 42.31%
High Blood Cholesterol: 11 people, 42.31%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.69%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 7.69%
Weight Loss: 1 person, 3.85%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 3.85%
Gait Disturbance: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Lyrica and have Obstructive uropathy?

- Check whether Obstructive uropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lyrica:

Lyrica (261,646 reports)

Browse all side effects of Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Obstructive uropathy:

Obstructive uropathy (148 drugs)

Browse all the conditions that are associated with Obstructive uropathy:

Obstructive uropathy (465 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Lyrica) and Lyrica (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.