1. Home
  2. Analysis
  3. Magnesium
  4. Brain-herniation

Magnesium and Brain herniation - a phase IV clinical study of FDA data

Summary:

Brain herniation is reported as a side effect among people who take Magnesium (magnesium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Osteoporosis.

The phase IV clinical study analyzes which people have Brain herniation when taking Magnesium. It is created by eHealthMe based on reports of 117,376 people who have side effects when taking Magnesium from the FDA, and is updated regularly.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,147 Magnesium users. Check the latest studies of Magnesium.

What is Brain herniation?

Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull) is found to be associated with 336 drugs and 976 conditions by eHealthMe. Check the latest studies of Brain herniation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

117,376 people reported to have side effects when taking Magnesium.
Among them, 28 people (0.02%) have Brain herniation.

Could Magnesium cause Brain herniation?

Among these 28 people:

How long have people been on Magnesium when they have Brain herniation? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Brain herniation when taking Magnesium? *

  • female: 57.14 %
  • male: 42.86 %

What is the age of people who have Brain herniation when taking Magnesium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.35 %
  • 20-29: 8.7 %
  • 30-39: 8.7 %
  • 40-49: 13.04 %
  • 50-59: 8.7 %
  • 60+: 56.52 %

What are other drugs people take besides Magnesium? *

  1. Prednisone: 5 people, 17.86%
  2. Tasigna: 4 people, 14.29%
  3. Enalapril Maleate: 4 people, 14.29%
  4. Pradaxa: 4 people, 14.29%
  5. Diazepam: 4 people, 14.29%
  6. Hydrochlorothiazide: 4 people, 14.29%
  7. Omeprazole: 4 people, 14.29%
  8. Crestor: 4 people, 14.29%
  9. Mirapex: 3 people, 10.71%
  10. Coreg: 3 people, 10.71%

What are other side effects people have besides Brain herniation? *

  1. Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 7 people, 25.00%
  2. Cerebral Haemorrhage (bleeding within the brain): 6 people, 21.43%
  3. Head Injury: 5 people, 17.86%
  4. Thrombocytopenia (decrease of platelets in blood): 5 people, 17.86%
  5. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 17.86%
  6. Hydrocephalus (water on the brain): 4 people, 14.29%
  7. Hepatomegaly (abnormal enlargement of the liver): 4 people, 14.29%
  8. Depressed Level Of Consciousness: 4 people, 14.29%
  9. Diarrhea: 4 people, 14.29%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 14.29%

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 17.86%
  2. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 5 people, 17.86%
  3. Osteoporosis (bones weak and more likely to break): 5 people, 17.86%
  4. Back Pain: 3 people, 10.71%
  5. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 10.71%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 10.71%
  7. Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 2 people, 7.14%
  8. Gastritis (inflammation of stomach): 2 people, 7.14%
  9. High Blood Pressure: 2 people, 7.14%
  10. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Magnesium and have Brain herniation?

- Check whether Brain herniation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Magnesium:

Brain herniation treatments and more:

How severe was Brain herniation and when was it recovered:

Expand to all the drugs that have ingredients of magnesium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain herniation:

Browse all the conditions that are associated with Brain herniation:

How the study uses the data?

The study uses data from the FDA. It is based on magnesium (the active ingredients of Magnesium) and Magnesium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.