Maprotiline hydrochloride and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Maprotiline hydrochloride (maprotiline hydrochloride), especially for people who are male, 30-39 old, also take Mirtazapine, and have Bipolar i disorder.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Maprotiline hydrochloride. It is created by eHealthMe based on reports of 234 people who have side effects when taking Maprotiline hydrochloride from the FDA, and is updated regularly.

What is Maprotiline hydrochloride?

Maprotiline hydrochloride has active ingredients of maprotiline hydrochloride. eHealthMe is studying from 242 Maprotiline hydrochloride users. Check the latest studies of Maprotiline hydrochloride.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,835 drugs and 4,500 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

234 people reported to have side effects when taking Maprotiline hydrochloride.
Among them, 15 people (6.41%) have Acute kidney failure.

Could Maprotiline hydrochloride cause Acute kidney failure?

Among these 15 people:

What is the gender of people who have Acute kidney failure when taking Maprotiline hydrochloride? *

female: 6.67 %
male: 93.33 %

What is the age of people who have Acute kidney failure when taking Maprotiline hydrochloride? *

What are other drugs people take besides Maprotiline hydrochloride? *

Estazolam: 4 people, 26.67%
Methadone Hydrochloride: 4 people, 26.67%
Tranxene: 4 people, 26.67%
Diazepam: 4 people, 26.67%
Mirtazapine: 4 people, 26.67%
Valproate Sodium: 3 people, 20.00%
Clonazepam: 3 people, 20.00%
Lipitor: 3 people, 20.00%
Lithium Carbonate: 3 people, 20.00%
Blopress: 3 people, 20.00%

What are other side effects people have besides Acute kidney failure? *

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 8 people, 53.33%
Confusional State: 6 people, 40.00%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 6 people, 40.00%
Poisoning: 4 people, 26.67%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 4 people, 26.67%
Loss Of Consciousness: 4 people, 26.67%
Drowsiness: 4 people, 26.67%
Anuria (failure of the kidneys to produce urine): 4 people, 26.67%
Fatigue (feeling of tiredness): 4 people, 26.67%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 3 people, 20.00%

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 20.00%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 20.00%
Thyroid Diseases: 1 person, 6.67%
Renal Disorder (kidney disease): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
Herpes Zoster: 1 person, 6.67%
Diabetes: 1 person, 6.67%
Depression: 1 person, 6.67%
Arrhythmias (irregular heartbeat): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Maprotiline hydrochloride and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Maprotiline hydrochloride:

Maprotiline hydrochloride (242 reports)

Browse all side effects of Maprotiline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,835 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,500 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on maprotiline hydrochloride (the active ingredients of Maprotiline hydrochloride) and Maprotiline hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.