Matulane and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Matulane (procarbazine hydrochloride), especially for people who are male, 60+ old, also take Tylenol, and have Brain neoplasm malignant.

The phase IV clinical study analyzes which people have Insomnia when taking Matulane. It is created by eHealthMe based on reports of 3,437 people who have side effects when taking Matulane from the FDA, and is updated regularly.

What is Matulane?

Matulane has active ingredients of procarbazine hydrochloride. eHealthMe is studying from 3,440 Matulane users. Check the latest studies of Matulane.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,118 drugs and 5,169 conditions by eHealthMe. Check the latest studies of Insomnia.

On Jul, 19, 2026

3,437 people reported to have side effects when taking Matulane.
Among them, 21 people (0.61%) have Insomnia.

Among these 21 people:

What is the gender of people who have Insomnia when taking Matulane? *

female: 36.84 %
male: 63.16 %

What is the age of people who have Insomnia when taking Matulane? *

What are other drugs people take besides Matulane? *

What are other side effects people have besides Insomnia? *

Fatigue (feeling of tiredness): 8 people, 38.10%
Constipation: 5 people, 23.81%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 19.05%
Nausea (feeling of having an urge to vomit): 3 people, 14.29%
Stress And Anxiety: 3 people, 14.29%
Hypoaesthesia (reduced sense of touch or sensation): 2 people, 9.52%
Weakness: 2 people, 9.52%
Itching: 2 people, 9.52%
Diarrhea: 2 people, 9.52%
White Blood Cell Count Decreased: 1 person, 4.76%

What are the existing conditions these people have? *

Brain Neoplasm Malignant (brain cancer tumour): 11 people, 52.38%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 19.05%
Hodgkin's Lymphoma (cancer originating from white blood cells): 3 people, 14.29%
Pyogenic Liver Abscess (liver abscess caused by bacteria): 1 person, 4.76%
Ill-Defined Disorder: 1 person, 4.76%
Brain Neoplasm Benign (non-cancerous tumour of brain): 1 person, 4.76%
B-Cell Lymphoma Stage Ii (blood cancer affecting b cells stage ii): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Matulane and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Matulane:

Matulane (3,440 reports)

Insomnia treatments and more:

Insomnia (438,078 reports)

Browse all side effects of Matulane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Insomnia (3,118 drugs)

Browse all the conditions that are associated with Insomnia:

Insomnia (5,169 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on procarbazine hydrochloride (the active ingredients of Matulane) and Matulane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.